Did Amino Acid Side Chain Reactivity Dictate the Composition and Timing of Aminoacyl-tRNA Synthetase Evolution?

The twenty amino acids in the standard genetic code were fixed prior to the last universal common ancestor (LUCA). Factors that guided this selection included establishment of pathways for their metabolic synthesis and the concomitant fixation of substrate specificities in the emerging aminoacyl-tRN...

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Detalles Bibliográficos
Autores principales: Hendrickson, Tamara L., Wood, Whitney N., Rathnayake, Udumbara M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001834/
https://www.ncbi.nlm.nih.gov/pubmed/33809136
http://dx.doi.org/10.3390/genes12030409

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