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Effect of Turmeric Concentrations on the Rate of Growth of Oral Bacteria—An In-Vitro Study
Background and Aim: The aim of this study was to evaluate the effect of varying concentrations of a turmeric solution on the growth rates of oral bacteria sampled from dental students. Methods: Bacterial cultures were grown overnight in aerobic conditions from plaque samples obtained from five test...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001890/ https://www.ncbi.nlm.nih.gov/pubmed/33804488 http://dx.doi.org/10.3390/dj9030026 |
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author | Yang, Yun Xuan Wu, Vicky Malak, Hadi Ahamed, Aliya Peer Lo, Aaron Abraham, Yannis Miller, Catherine |
author_facet | Yang, Yun Xuan Wu, Vicky Malak, Hadi Ahamed, Aliya Peer Lo, Aaron Abraham, Yannis Miller, Catherine |
author_sort | Yang, Yun Xuan |
collection | PubMed |
description | Background and Aim: The aim of this study was to evaluate the effect of varying concentrations of a turmeric solution on the growth rates of oral bacteria sampled from dental students. Methods: Bacterial cultures were grown overnight in aerobic conditions from plaque samples obtained from five test subjects. With the exception of the control, samples were exposed to different treatments; including chlorhexidine gluconate 2 mg/mL, prepared turmeric solution (TS) mouthwash: TS 0.25 mL (7.375 mg/mL), TS 0.5 mL (14.75 mg/mL), and TS 1 mL (29.50 mg/mL). Growth rate of the bacterial cultures were assessed by monitoring changes in optical density readings at 600 nm at hourly intervals for a six-hour period. The data were plotted and the exponential trend was used to calculate individual rates of growth. Data was analyzed using a one-way ANOVA with the significance confirmed using the Tukey-HSD test. Results: Growth observed in the bacteria exposed to the turmeric solution, was significantly greater (p < 0.05) when compared with the bacteria exposed to the medium alone. There was a significant difference found between the bacterial growth rate of the 1 mL turmeric solution against the growth rate of the bacteria in the 0.25 and 0.5 mL turmeric solutions. Conclusion: Comparison of growth rates of oral bacteria suggested that turmeric solutions of concentrations between 7.357 and 29.5 mg/mL (0.25–1 mL) were unlikely to exhibit bacteriostatic or bactericidal properties, and, conversely, increased bacterial growth. Considering this result, it is unlikely that turmeric mouthwash made from store-bought turmeric would have any antibacterial effects against oral bacteria, and may even promote bacterial growth. |
format | Online Article Text |
id | pubmed-8001890 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-80018902021-03-28 Effect of Turmeric Concentrations on the Rate of Growth of Oral Bacteria—An In-Vitro Study Yang, Yun Xuan Wu, Vicky Malak, Hadi Ahamed, Aliya Peer Lo, Aaron Abraham, Yannis Miller, Catherine Dent J (Basel) Article Background and Aim: The aim of this study was to evaluate the effect of varying concentrations of a turmeric solution on the growth rates of oral bacteria sampled from dental students. Methods: Bacterial cultures were grown overnight in aerobic conditions from plaque samples obtained from five test subjects. With the exception of the control, samples were exposed to different treatments; including chlorhexidine gluconate 2 mg/mL, prepared turmeric solution (TS) mouthwash: TS 0.25 mL (7.375 mg/mL), TS 0.5 mL (14.75 mg/mL), and TS 1 mL (29.50 mg/mL). Growth rate of the bacterial cultures were assessed by monitoring changes in optical density readings at 600 nm at hourly intervals for a six-hour period. The data were plotted and the exponential trend was used to calculate individual rates of growth. Data was analyzed using a one-way ANOVA with the significance confirmed using the Tukey-HSD test. Results: Growth observed in the bacteria exposed to the turmeric solution, was significantly greater (p < 0.05) when compared with the bacteria exposed to the medium alone. There was a significant difference found between the bacterial growth rate of the 1 mL turmeric solution against the growth rate of the bacteria in the 0.25 and 0.5 mL turmeric solutions. Conclusion: Comparison of growth rates of oral bacteria suggested that turmeric solutions of concentrations between 7.357 and 29.5 mg/mL (0.25–1 mL) were unlikely to exhibit bacteriostatic or bactericidal properties, and, conversely, increased bacterial growth. Considering this result, it is unlikely that turmeric mouthwash made from store-bought turmeric would have any antibacterial effects against oral bacteria, and may even promote bacterial growth. MDPI 2021-03-01 /pmc/articles/PMC8001890/ /pubmed/33804488 http://dx.doi.org/10.3390/dj9030026 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ). |
spellingShingle | Article Yang, Yun Xuan Wu, Vicky Malak, Hadi Ahamed, Aliya Peer Lo, Aaron Abraham, Yannis Miller, Catherine Effect of Turmeric Concentrations on the Rate of Growth of Oral Bacteria—An In-Vitro Study |
title | Effect of Turmeric Concentrations on the Rate of Growth of Oral Bacteria—An In-Vitro Study |
title_full | Effect of Turmeric Concentrations on the Rate of Growth of Oral Bacteria—An In-Vitro Study |
title_fullStr | Effect of Turmeric Concentrations on the Rate of Growth of Oral Bacteria—An In-Vitro Study |
title_full_unstemmed | Effect of Turmeric Concentrations on the Rate of Growth of Oral Bacteria—An In-Vitro Study |
title_short | Effect of Turmeric Concentrations on the Rate of Growth of Oral Bacteria—An In-Vitro Study |
title_sort | effect of turmeric concentrations on the rate of growth of oral bacteria—an in-vitro study |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001890/ https://www.ncbi.nlm.nih.gov/pubmed/33804488 http://dx.doi.org/10.3390/dj9030026 |
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