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Effect of Turmeric Concentrations on the Rate of Growth of Oral Bacteria—An In-Vitro Study

Background and Aim: The aim of this study was to evaluate the effect of varying concentrations of a turmeric solution on the growth rates of oral bacteria sampled from dental students. Methods: Bacterial cultures were grown overnight in aerobic conditions from plaque samples obtained from five test...

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Autores principales: Yang, Yun Xuan, Wu, Vicky, Malak, Hadi, Ahamed, Aliya Peer, Lo, Aaron, Abraham, Yannis, Miller, Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001890/
https://www.ncbi.nlm.nih.gov/pubmed/33804488
http://dx.doi.org/10.3390/dj9030026
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author Yang, Yun Xuan
Wu, Vicky
Malak, Hadi
Ahamed, Aliya Peer
Lo, Aaron
Abraham, Yannis
Miller, Catherine
author_facet Yang, Yun Xuan
Wu, Vicky
Malak, Hadi
Ahamed, Aliya Peer
Lo, Aaron
Abraham, Yannis
Miller, Catherine
author_sort Yang, Yun Xuan
collection PubMed
description Background and Aim: The aim of this study was to evaluate the effect of varying concentrations of a turmeric solution on the growth rates of oral bacteria sampled from dental students. Methods: Bacterial cultures were grown overnight in aerobic conditions from plaque samples obtained from five test subjects. With the exception of the control, samples were exposed to different treatments; including chlorhexidine gluconate 2 mg/mL, prepared turmeric solution (TS) mouthwash: TS 0.25 mL (7.375 mg/mL), TS 0.5 mL (14.75 mg/mL), and TS 1 mL (29.50 mg/mL). Growth rate of the bacterial cultures were assessed by monitoring changes in optical density readings at 600 nm at hourly intervals for a six-hour period. The data were plotted and the exponential trend was used to calculate individual rates of growth. Data was analyzed using a one-way ANOVA with the significance confirmed using the Tukey-HSD test. Results: Growth observed in the bacteria exposed to the turmeric solution, was significantly greater (p < 0.05) when compared with the bacteria exposed to the medium alone. There was a significant difference found between the bacterial growth rate of the 1 mL turmeric solution against the growth rate of the bacteria in the 0.25 and 0.5 mL turmeric solutions. Conclusion: Comparison of growth rates of oral bacteria suggested that turmeric solutions of concentrations between 7.357 and 29.5 mg/mL (0.25–1 mL) were unlikely to exhibit bacteriostatic or bactericidal properties, and, conversely, increased bacterial growth. Considering this result, it is unlikely that turmeric mouthwash made from store-bought turmeric would have any antibacterial effects against oral bacteria, and may even promote bacterial growth.
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spelling pubmed-80018902021-03-28 Effect of Turmeric Concentrations on the Rate of Growth of Oral Bacteria—An In-Vitro Study Yang, Yun Xuan Wu, Vicky Malak, Hadi Ahamed, Aliya Peer Lo, Aaron Abraham, Yannis Miller, Catherine Dent J (Basel) Article Background and Aim: The aim of this study was to evaluate the effect of varying concentrations of a turmeric solution on the growth rates of oral bacteria sampled from dental students. Methods: Bacterial cultures were grown overnight in aerobic conditions from plaque samples obtained from five test subjects. With the exception of the control, samples were exposed to different treatments; including chlorhexidine gluconate 2 mg/mL, prepared turmeric solution (TS) mouthwash: TS 0.25 mL (7.375 mg/mL), TS 0.5 mL (14.75 mg/mL), and TS 1 mL (29.50 mg/mL). Growth rate of the bacterial cultures were assessed by monitoring changes in optical density readings at 600 nm at hourly intervals for a six-hour period. The data were plotted and the exponential trend was used to calculate individual rates of growth. Data was analyzed using a one-way ANOVA with the significance confirmed using the Tukey-HSD test. Results: Growth observed in the bacteria exposed to the turmeric solution, was significantly greater (p < 0.05) when compared with the bacteria exposed to the medium alone. There was a significant difference found between the bacterial growth rate of the 1 mL turmeric solution against the growth rate of the bacteria in the 0.25 and 0.5 mL turmeric solutions. Conclusion: Comparison of growth rates of oral bacteria suggested that turmeric solutions of concentrations between 7.357 and 29.5 mg/mL (0.25–1 mL) were unlikely to exhibit bacteriostatic or bactericidal properties, and, conversely, increased bacterial growth. Considering this result, it is unlikely that turmeric mouthwash made from store-bought turmeric would have any antibacterial effects against oral bacteria, and may even promote bacterial growth. MDPI 2021-03-01 /pmc/articles/PMC8001890/ /pubmed/33804488 http://dx.doi.org/10.3390/dj9030026 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ).
spellingShingle Article
Yang, Yun Xuan
Wu, Vicky
Malak, Hadi
Ahamed, Aliya Peer
Lo, Aaron
Abraham, Yannis
Miller, Catherine
Effect of Turmeric Concentrations on the Rate of Growth of Oral Bacteria—An In-Vitro Study
title Effect of Turmeric Concentrations on the Rate of Growth of Oral Bacteria—An In-Vitro Study
title_full Effect of Turmeric Concentrations on the Rate of Growth of Oral Bacteria—An In-Vitro Study
title_fullStr Effect of Turmeric Concentrations on the Rate of Growth of Oral Bacteria—An In-Vitro Study
title_full_unstemmed Effect of Turmeric Concentrations on the Rate of Growth of Oral Bacteria—An In-Vitro Study
title_short Effect of Turmeric Concentrations on the Rate of Growth of Oral Bacteria—An In-Vitro Study
title_sort effect of turmeric concentrations on the rate of growth of oral bacteria—an in-vitro study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001890/
https://www.ncbi.nlm.nih.gov/pubmed/33804488
http://dx.doi.org/10.3390/dj9030026
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