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Differential Involvement of ACKR3 C-Tail in β-Arrestin Recruitment, Trafficking and Internalization

Background: The atypical chemokine receptor 3 (ACKR3) belongs to the superfamily of G protein-coupled receptors (GPCRs). Unlike classical GPCRs, this receptor does not activate G proteins in most cell types but recruits β-arrestins upon activation. ACKR3 plays an important role in cancer and vascula...

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Detalles Bibliográficos
Autores principales: Zarca, Aurélien, Perez, Claudia, van den Bor, Jelle, Bebelman, Jan Paul, Heuninck, Joyce, de Jonker, Rianna J. F., Durroux, Thierry, Vischer, Henry F., Siderius, Marco, Smit, Martine J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8002179/
https://www.ncbi.nlm.nih.gov/pubmed/33799570
http://dx.doi.org/10.3390/cells10030618

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