Cargando…

Functional Genetic Variants in ATG10 Are Associated with Acute Myeloid Leukemia

SIMPLE SUMMARY: Acute myeloid leukemia (AML) is a hematological neoplasm with a very poor survival rate. To date, diagnostic tools to monitor individuals at higher risk of developing AML are scarce. Single nucleotide polymorphisms (SNPs) have emerged as good candidates for disease prevention. AML is...

Descripción completa

Detalles Bibliográficos
Autores principales:	Castro, Isabel, Sampaio-Marques, Belém, C. Areias, Anabela, Sousa, Hugo, Fernandes, Ângela, Sanchez-Maldonado, José Manuel, Cunha, Cristina, Carvalho, Agostinho, Sainz, Juan, Ludovico, Paula
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8002222/ https://www.ncbi.nlm.nih.gov/pubmed/33809750 http://dx.doi.org/10.3390/cancers13061344

Ejemplares similares

Targeting Metabolic Reprogramming in Acute Myeloid Leukemia
por: Castro, Isabel, et al.
Publicado: (2019)

Proteolytic systems and AMP-activated protein kinase are critical targets of acute myeloid leukemia therapeutic approaches
por: Fernandes, Ângela, et al.
Publicado: (2014)

Current and Emerging Techniques for Diagnosis and MRD Detection in AML: A Comprehensive Narrative Review
por: Teixeira, Alexandra, et al.
Publicado: (2023)

Signalling mechanisms that regulate metabolic profile and autophagy of acute myeloid leukaemia cells
por: Pereira, Olga, et al.
Publicado: (2018)

Sirtuins and Proteolytic Systems: Implications for Pathogenesis of Synucleinopathies
por: Sampaio-Marques, Belém, et al.
Publicado: (2015)

Longevity pathways and maintenance of the proteome: the role of autophagy and mitophagy during yeast ageing
por: Sampaio-Marques, Belém, et al.
Publicado: (2014)

MicroRNA-143 sensitizes acute myeloid leukemia cells to cytarabine via targeting ATG7- and ATG2B-dependent autophagy
por: Zhang, Hao, et al.
Publicado: (2020)

Caloric restriction rescues yeast cells from alpha-synuclein toxicity through autophagic control of proteostasis
por: Sampaio-Marques, Belém, et al.
Publicado: (2018)

Involvement of Yeast HSP90 Isoforms in Response to Stress and Cell Death Induced by Acetic Acid
por: Silva, Alexandra, et al.
Publicado: (2013)

Noncanonical E2 recruitment by the autophagy E1 revealed by Atg7–Atg3 and Atg7–Atg10 structures
por: Kaiser, Stephen E., et al.
Publicado: (2012)

Transcriptomic and chemogenomic analyses unveil the essential role of Com2-regulon in response and tolerance of Saccharomyces cerevisiae to stress induced by sulfur dioxide
por: Lage, Patrícia, et al.
Publicado: (2019)

Effects of Intermittent Fasting on Regulation of Metabolic Homeostasis: A Systematic Review and Meta-Analysis in Health and Metabolic-Related Disorders
por: Silva, Ana Inês, et al.
Publicado: (2023)

Impact of CMV reactivation on relapse of acute myeloid leukemia after HCT is dependent on disease stage and ATG
por: Turki, Amin T., et al.
Publicado: (2021)

Mitochondrial proteomics of the acetic acid - induced programmed cell death response in a highly tolerant Zygosaccharomyces bailii - derived hybrid strain
por: Guerreiro, Joana F., et al.
Publicado: (2016)

Atg5-dependent autophagy contributes to the development of acute myeloid leukemia in an MLL-AF9-driven mouse model
por: Liu, Qiang, et al.
Publicado: (2016)

The Yeast Protein Kinase Sch9 Functions as a Central Nutrient-Responsive Hub That Calibrates Metabolic and Stress-Related Responses
por: Caligaris, Marco, et al.
Publicado: (2023)

Acute myeloid leukemia with variant t(8;10;21)
por: Bacova, Barbora, et al.
Publicado: (2022)

α‐Synuclein toxicity in yeast and human cells is caused by cell cycle re‐entry and autophagy degradation of ribonucleotide reductase 1
por: Sampaio‐Marques, Belém, et al.
Publicado: (2019)

Epidemiological evaluation and survival of children with acute myeloid leukemia
por: Morais, Rahuany Velleda de, et al.
Publicado: (2020)

miRNAs as prognostic predictors in acute myeloid leukemia
por: Machado-Neto, João Agostinho, et al.
Publicado: (2023)

Proteomic Analysis of the Action of the Mycobacterium ulcerans Toxin Mycolactone: Targeting Host Cells Cytoskeleton and Collagen
por: Gama, José B., et al.
Publicado: (2014)

MicroRNA-10a/b are regulators of myeloid differentiation and acute myeloid leukemia
por: Bi, Laixi, et al.
Publicado: (2018)

Different effects of Atg2 and Atg18 mutations on Atg8a and Atg9 trafficking during starvation in Drosophila()
por: Nagy, Péter, et al.
Publicado: (2014)

Association between Immunophenotypic Parameters and Molecular Alterations in Acute Myeloid Leukemia
por: Pessoa, Flávia Melo Cunha de Pinho, et al.
Publicado: (2023)

PB1826: CELLULAR AND MOLECULAR CHARACTERIZATION OF THE ANTINEOPLASTIC EFFECTS OF CEPHALOCHROMIN IN MODELS OF ACUTE MYELOID LEUKEMIA
por: Nascimento, Mariane Cristina Do, et al.
Publicado: (2023)

Closing the loop: Three musketeers of autophagy-ATG2, ATG18a, and ATG9
por: Mishra, Divya
Publicado: (2023)

Crystallization of the Atg12–Atg5 conjugate bound to Atg16 by the free-interface diffusion method
por: Noda, Nobuo N., et al.
Publicado: (2008)

Prognostic role of ACTL10 in Cytogenetic Normal Acute Myeloid Leukemia
por: Lai, Rui, et al.
Publicado: (2020)

Overexpression of HOXA10 is associated with unfavorable prognosis of acute myeloid leukemia
por: Guo, Chao, et al.
Publicado: (2020)

Oxidation of Atg3 and Atg7 mediates inhibition of autophagy
por: Frudd, Karen, et al.
Publicado: (2018)

A semisynthetic Atg3 reveals that acetylation promotes Atg3 membrane binding and Atg8 lipidation
por: Li, Yi-Tong, et al.
Publicado: (2017)

Caffeine Consumption Prevents Diabetes-Induced Memory Impairment and Synaptotoxicity in the Hippocampus of NONcZNO10/LTJ Mice
por: Duarte, João M. N., et al.
Publicado: (2012)

Salvage treatment for refractory or relapsed acute myeloid leukemia: a 10-year single-center experience
por: da Silva, Wellington Fernandes, et al.
Publicado: (2020)

PB1847: ACUTE MYELOID LEUKEMIA – IS IT MORE BESIDES GENETIC ABNORMALITIES?
por: Urbano, M., et al.
Publicado: (2022)

Genomic Mechanisms Influencing Outcome in Chronic Myeloid Leukemia
por: Fernandes, Adelina, et al.
Publicado: (2022)

Influence of Atg5 Mutation in SLE Depends on Functional IL-10 Genotype
por: López, Patricia, et al.
Publicado: (2013)

Identifying a selective inhibitor of autophagy that targets ATG12-ATG3 protein-protein interaction
por: Nuta, Gal Chaim, et al.
Publicado: (2023)

Comparative evolutionary genomics of the HADH2 gene encoding Aβ-binding alcohol dehydrogenase/17β-hydroxysteroid dehydrogenase type 10 (ABAD/HSD10)
por: Marques, Alexandra T, et al.
Publicado: (2006)

Processing speed mediates the association between physical activity and executive functioning in elderly adults
por: Silva-Fernandes, Anabela, et al.
Publicado: (2022)

Corrigendum: Processing speed mediates the association between physical activity and executive functioning in elderly adults
por: Silva-Fernandes, Anabela, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_7eru29n6dn34ra8ippkeickk82