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Dielectric Properties of Ovine Heart at Microwave Frequencies

Accurate knowledge of the dielectric properties of biological tissues is important in dosimetry studies and for medical diagnostic, monitoring and therapeutic technologies. In particular, the dielectric properties of the heart are used in numerical simulations of radiofrequency and microwave heart a...

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Autores principales: Ištuk, Niko, Porter, Emily, O’Loughlin, Declan, McDermott, Barry, Santorelli, Adam, Abedi, Soroush, Joachimowicz, Nadine, Roussel, Hélène, O’Halloran, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8002248/
https://www.ncbi.nlm.nih.gov/pubmed/33809672
http://dx.doi.org/10.3390/diagnostics11030531
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author Ištuk, Niko
Porter, Emily
O’Loughlin, Declan
McDermott, Barry
Santorelli, Adam
Abedi, Soroush
Joachimowicz, Nadine
Roussel, Hélène
O’Halloran, Martin
author_facet Ištuk, Niko
Porter, Emily
O’Loughlin, Declan
McDermott, Barry
Santorelli, Adam
Abedi, Soroush
Joachimowicz, Nadine
Roussel, Hélène
O’Halloran, Martin
author_sort Ištuk, Niko
collection PubMed
description Accurate knowledge of the dielectric properties of biological tissues is important in dosimetry studies and for medical diagnostic, monitoring and therapeutic technologies. In particular, the dielectric properties of the heart are used in numerical simulations of radiofrequency and microwave heart ablation. In one recent study, it was demonstrated that the dielectric properties of different components of the heart can vary considerably, contrary to previous literature that treated the heart as a homogeneous organ with measurements that ignored the anatomical location. Therefore, in this study, we record and report the dielectric properties of the heart as a heterogeneous organ. We measured the dielectric properties at different locations inside and outside of the heart over the 500 MHz to 20 GHz frequency range. Different parts of the heart were identified based on the anatomy of the heart and their function; they include the epicardium, endocardium, myocardium, exterior and interior surfaces of atrial appendage, and the luminal surface of the great vessels. The measured dielectric properties for each part of the heart are reported at both a single frequency (2.4 GHz), which is of interest in microwave medical applications, and as parameters of a broadband Debye model. The results show that in terms of dielectric properties, different parts of the heart should not be considered the same, with more than 25% difference in dielectric properties between some parts. The specific Debye models and single frequency dielectric properties from this study can be used to develop more detailed models of the heart to be used in electromagnetic modeling.
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spelling pubmed-80022482021-03-28 Dielectric Properties of Ovine Heart at Microwave Frequencies Ištuk, Niko Porter, Emily O’Loughlin, Declan McDermott, Barry Santorelli, Adam Abedi, Soroush Joachimowicz, Nadine Roussel, Hélène O’Halloran, Martin Diagnostics (Basel) Article Accurate knowledge of the dielectric properties of biological tissues is important in dosimetry studies and for medical diagnostic, monitoring and therapeutic technologies. In particular, the dielectric properties of the heart are used in numerical simulations of radiofrequency and microwave heart ablation. In one recent study, it was demonstrated that the dielectric properties of different components of the heart can vary considerably, contrary to previous literature that treated the heart as a homogeneous organ with measurements that ignored the anatomical location. Therefore, in this study, we record and report the dielectric properties of the heart as a heterogeneous organ. We measured the dielectric properties at different locations inside and outside of the heart over the 500 MHz to 20 GHz frequency range. Different parts of the heart were identified based on the anatomy of the heart and their function; they include the epicardium, endocardium, myocardium, exterior and interior surfaces of atrial appendage, and the luminal surface of the great vessels. The measured dielectric properties for each part of the heart are reported at both a single frequency (2.4 GHz), which is of interest in microwave medical applications, and as parameters of a broadband Debye model. The results show that in terms of dielectric properties, different parts of the heart should not be considered the same, with more than 25% difference in dielectric properties between some parts. The specific Debye models and single frequency dielectric properties from this study can be used to develop more detailed models of the heart to be used in electromagnetic modeling. MDPI 2021-03-16 /pmc/articles/PMC8002248/ /pubmed/33809672 http://dx.doi.org/10.3390/diagnostics11030531 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ).
spellingShingle Article
Ištuk, Niko
Porter, Emily
O’Loughlin, Declan
McDermott, Barry
Santorelli, Adam
Abedi, Soroush
Joachimowicz, Nadine
Roussel, Hélène
O’Halloran, Martin
Dielectric Properties of Ovine Heart at Microwave Frequencies
title Dielectric Properties of Ovine Heart at Microwave Frequencies
title_full Dielectric Properties of Ovine Heart at Microwave Frequencies
title_fullStr Dielectric Properties of Ovine Heart at Microwave Frequencies
title_full_unstemmed Dielectric Properties of Ovine Heart at Microwave Frequencies
title_short Dielectric Properties of Ovine Heart at Microwave Frequencies
title_sort dielectric properties of ovine heart at microwave frequencies
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8002248/
https://www.ncbi.nlm.nih.gov/pubmed/33809672
http://dx.doi.org/10.3390/diagnostics11030531
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