Epigallocatechin-3-Gallate Plus Omega-3 Restores the Mitochondrial Complex I and F(0)F(1)-ATP Synthase Activities in PBMCs of Young Children with Down Syndrome: A Pilot Study of Safety and Efficacy

Down syndrome (DS) is a major genetic cause of intellectual disability. DS pathogenesis has not been fully elucidated, and no specific pharmacological therapy is available. DYRK1A overexpression, oxidative stress and mitochondrial dysfunction were described in trisomy 21. Epigallocatechin-3-gallate...

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Detalles Bibliográficos
Autores principales: Scala, Iris, Valenti, Daniela, Scotto D’Aniello, Valentina, Marino, Maria, Riccio, Maria Pia, Bravaccio, Carmela, Vacca, Rosa Anna, Strisciuglio, Pietro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8002266/
https://www.ncbi.nlm.nih.gov/pubmed/33809669
http://dx.doi.org/10.3390/antiox10030469

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