Cargando…

Synthesis and Biological Activity Evaluation of Coumarin-3-Carboxamide Derivatives

A series of novel coumarin-3-carboxamide derivatives were designed and synthesized to evaluate their biological activities. The compounds showed little to no activity against gram-positive and gram-negative bacteria but specifically showed potential to inhibit the growth of cancer cells. In particul...

Descripción completa

Detalles Bibliográficos
Autores principales:	Phutdhawong, Weerachai, Chuenchid, Apiwat, Taechowisan, Thongchai, Sirirak, Jitnapa, Phutdhawong, Waya S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8002271/ https://www.ncbi.nlm.nih.gov/pubmed/33809679 http://dx.doi.org/10.3390/molecules26061653

Ejemplares similares

2,5-Diketopiperazine Derivatives as Potential Anti-Influenza (H5N2) Agents: Synthesis, Biological Evaluation, and Molecular Docking Study
por: Winyakul, Chanakan, et al.
Publicado: (2022)

Synthesis and Investigation of Tetrahydro-β-carboline Derivatives as Inhibitors of Plant Pathogenic Fungi
por: Buaban, Koonchira, et al.
Publicado: (2021)

Synthesis and inhibitory activity of N-acetylpyrrolidine derivatives on α-glucosidase and α-amylase
por: Sansenya, Sompong, et al.
Publicado: (2020)

Electrocoagulation of Palm Oil Mill Effluent
por: Agustin, Melissa B., et al.
Publicado: (2008)

Facile Microwave-assisted Synthesis of 9,10-Dihydro-9,10-ethanoanthracene-11-carboxylic acid Methyl Ester
por: Phutdhawong, Weerachai, et al.
Publicado: (2005)

Novel Coumarin 7-Carboxamide/Sulfonamide Derivatives as Potential Fungicidal Agents: Design, Synthesis, and Biological Evaluation
por: Zhang, Shu-Guang, et al.
Publicado: (2022)

Synthesis and Anticancer Evaluation of Novel 7-Aza-Coumarine-3-Carboxamides
por: Trifonov, Alexey V., et al.
Publicado: (2023)

Total Synthesis and the Biological Activities of (±)-Norannuradhapurine
por: Nimgirawath, Surachai, et al.
Publicado: (2008)

Crystal structures of three 6-substituted coumarin-3-carboxamide derivatives
por: Gomes, Lígia R., et al.
Publicado: (2016)

Synthesis and Biological Evaluation of Some New Coumarin Derivatives
por: Al-Haiza, M.A., et al.
Publicado: (2003)

Total Synthesis and Antimicrobial Activity of (±)-Laurelliptinhexadecan-1-one and (±)-Laurelliptinoctadecan-1-one
por: Nimgirawath, Surachai, et al.
Publicado: (2008)

Piperidine-Iodine as Efficient Dual Catalyst for the One-Pot, Three-Component Synthesis of Coumarin-3-Carboxamides
por: Velasco, Manuel, et al.
Publicado: (2022)

Diarylamine-Guided Carboxamide Derivatives: Synthesis, Biological Evaluation, and Potential Mechanism of Action
por: Ke, Shaoyong, et al.
Publicado: (2022)

Convenient synthesis, characterization and biological evaluation of novel 1-phenylcyclopropane carboxamide derivatives
por: Mahesh, Panasa, et al.
Publicado: (2023)

Synthesis and Biological Activity of Triterpene–Coumarin Conjugates
por: Vega-Granados, Karina, et al.
Publicado: (2021)

Synthesis and Biological Evaluation of N-Alkyl-3-(alkylamino)-pyrazine-2-carboxamides
por: Semelkova, Lucia, et al.
Publicado: (2015)

Substituted N-Benzylpyrazine-2-carboxamides: Synthesis and Biological Evaluation (†)
por: Servusová, Barbora, et al.
Publicado: (2012)

Coumarin-piperazine derivatives as biologically active compounds
por: Ostrowska, Kinga
Publicado: (2020)

Synthesis and biological evaluation of 3–(4-aminophenyl)-coumarin derivatives as potential anti-Alzheimer’s disease agents
por: Hu, Yu-Heng, et al.
Publicado: (2019)

Synthesis and Biological Evaluation of Novel Thiazolyl-Coumarin Derivatives as Potent Histone Deacetylase Inhibitors with Antifibrotic Activity
por: Pardo-Jiménez, Viviana, et al.
Publicado: (2019)

Synthesis and Vasorelaxant Activity of Nitrate−Coumarin Derivatives
por: Matos, Maria João, et al.
Publicado: (2022)

Design, Synthesis and Biological Evaluation of Novel 4-Substituted Coumarin Derivatives as Antitumor Agents
por: An, Ran, et al.
Publicado: (2018)

Design, Synthesis and Preliminary Biological Evaluation of Benzylsulfone Coumarin Derivatives as Anti-Cancer Agents
por: Wang, Tao, et al.
Publicado: (2019)

Design, synthesis, biological evaluation and QSAR analysis of novel N-substituted benzimidazole derived carboxamides
por: Beč, Anja, et al.
Publicado: (2022)

Design, synthesis, molecular docking studies and biological evaluation of thiazole carboxamide derivatives as COX inhibitors
por: Hawash, Mohammed, et al.
Publicado: (2023)

Design and Comparative Evaluation of Vancomycin HCl-Loaded Rosin-Based In Situ Forming Gel and Microparticles
por: Chuenbarn, Tiraniti, et al.
Publicado: (2022)

Derivatives of 3-Aminopyrazine-2-carboxamides: Synthesis, Antimicrobial Evaluation, and in Vitro Cytotoxicity
por: Bouz, Ghada, et al.
Publicado: (2019)

Biological synthesis of coumarins in Escherichia coli
por: Yang, So-Mi, et al.
Publicado: (2015)

Recent Advances in Biologically Active Coumarins from Marine Sources: Synthesis and Evaluation
por: Fernández-Peña, Laura, et al.
Publicado: (2022)

Biological Activity of Coumarin Derivatives as Anti-Leishmanial Agents
por: Mandlik, Vineetha, et al.
Publicado: (2016)

Synthesis of Novel Pyrazinamide Derivatives Based on 3-Chloropyrazine-2-carboxamide and Their Antimicrobial Evaluation
por: Jandourek, Ondrej, et al.
Publicado: (2017)

3-Substituted N-Benzylpyrazine-2-carboxamide Derivatives: Synthesis, Antimycobacterial and Antibacterial Evaluation
por: Semelková, Lucia, et al.
Publicado: (2017)

A New and Efficient Method for the Synthesis of Novel 3-Acetyl Coumarins Oxadiazoles Derivatives with Expected Biological Activity
por: Sulaiman Al-Ayed, Abdullah, et al.
Publicado: (2014)

Asymmetric organocatalyzed synthesis of coumarin derivatives
por: Moreira, Natália Menezes, et al.
Publicado: (2021)

Synthesis and Evaluation of Coumarin-Chalcone Derivatives as α-Glucosidase Inhibitors
por: Hu, Chun-Mei, et al.
Publicado: (2022)

Synthesis, docking studies, biological activity of carbon monoxide release molecules based on coumarin derivatives
por: Liu, Huapeng, et al.
Publicado: (2022)

Synthesis and biological evaluation of new 3-substituted coumarin derivatives as selective inhibitors of human carbonic anhydrase IX and XII
por: Mahammad Ghouse, Shaik, et al.
Publicado: (2023)

Design, Synthesis and Biological Evaluation of Novel Coumarin-Based Hydroxamate Derivatives as Histone Deacetylase (Hdac) Inhibitors with Antitumor Activities
por: Yang, Feifei, et al.
Publicado: (2019)

Synthesis, Biological Evaluation, and In Silico Modeling of N-Substituted Quinoxaline-2-Carboxamides
por: Bouz, Ghada, et al.
Publicado: (2021)

Synthesis and biological evaluation of coumarin-quinone hybrids as multifunctional bioactive agents
por: Pangal, Anees, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_kf8murfd6qgouv94nikhbt80hu