Cargando…
Heterogeneity in Signaling Pathway Activity within Primary and between Primary and Metastatic Breast Cancer
SIMPLE SUMMARY: Personalized breast cancer treatment with targeted therapy (e.g., tamoxifen or PI3K inhibitors) requires identification of responder patients. Phenotypical heterogeneity within the primary, and between primary tumor and metastases, may however interfere with response to therapy, if b...
Autores principales: | Inda, Márcia A., van Swinderen, Paul, van Brussel, Anne, Moelans, Cathy B., Verhaegh, Wim, van Zon, Hans, den Biezen, Eveline, Bikker, Jan Willem, van Diest, Paul J., van de Stolpe, Anja |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8002348/ https://www.ncbi.nlm.nih.gov/pubmed/33809754 http://dx.doi.org/10.3390/cancers13061345 |
Ejemplares similares
-
ER and PI3K Pathway Activity in Primary ER Positive Breast Cancer Is Associated with Progression-Free Survival of Metastatic Patients under First-Line Tamoxifen
por: M. Sieuwerts, Anieta, et al.
Publicado: (2020) -
Enabling precision medicine by unravelling disease pathophysiology: quantifying signal transduction pathway activity across cell and tissue types
por: Stolpe, Anja van de, et al.
Publicado: (2019) -
Publisher Correction: Enabling precision medicine by unravelling disease pathophysiology: quantifying signal transduction pathway activity across cell and tissue types
por: van de Stolpe, Anja, et al.
Publicado: (2020) -
Knowledge-based computational models
por: Verhaegh, Wim, et al.
Publicado: (2014) -
ESR1 Amplification in Breast Cancer by Optimized RNase FISH: Frequent but Low-Level and Heterogeneous
por: Moelans, Cathy B., et al.
Publicado: (2013)