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Clinical Observation of Allergic Conjunctival Diseases with Portable and Recordable Slit-Lamp Device

Background: The incidence of allergic conjunctival diseases (ACDs) is gradually increasing worldwide. Both ophthalmologists and non-ophthalmologists prescribe eye drops to treat ACDs; however, there are many cases which are treated without sufficient examination and diagnosis of the eyes. We have in...

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Autores principales: Yazu, Hiroyuki, Shimizu, Eisuke, Sato, Shinri, Aketa, Naohiko, Katayama, Taiichiro, Yokoiwa, Ryota, Sato, Yasunori, Fukagawa, Kazumi, Ogawa, Yoko, Tsubota, Kazuo, Fujishima, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8002473/
https://www.ncbi.nlm.nih.gov/pubmed/33802736
http://dx.doi.org/10.3390/diagnostics11030535
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author Yazu, Hiroyuki
Shimizu, Eisuke
Sato, Shinri
Aketa, Naohiko
Katayama, Taiichiro
Yokoiwa, Ryota
Sato, Yasunori
Fukagawa, Kazumi
Ogawa, Yoko
Tsubota, Kazuo
Fujishima, Hiroshi
author_facet Yazu, Hiroyuki
Shimizu, Eisuke
Sato, Shinri
Aketa, Naohiko
Katayama, Taiichiro
Yokoiwa, Ryota
Sato, Yasunori
Fukagawa, Kazumi
Ogawa, Yoko
Tsubota, Kazuo
Fujishima, Hiroshi
author_sort Yazu, Hiroyuki
collection PubMed
description Background: The incidence of allergic conjunctival diseases (ACDs) is gradually increasing worldwide. Both ophthalmologists and non-ophthalmologists prescribe eye drops to treat ACDs; however, there are many cases which are treated without sufficient examination and diagnosis of the eyes. We have invented a portable, recordable, and smartphone-attachable slit-lamp device—Smart Eye Camera (SEC). The purpose of this study was to compare the diagnostic abilities of ACDs between the SEC and the conventional, non-portable slit-lamp microscope. Methods: This prospective observational study included 32 eyes of 17 Japanese patients (mean age: 21.5 ± 14.8 years; range: 11–51 years; female: 5). The severity of 10 objective signs in the palpebral conjunctiva, bulbar conjunctiva, limbus, and cornea were scored on a grading scale of 0 to 4 (0 = normal; 1+ = mild; 2+ = moderate; 3+ = severe), respectively. First, the conventional slit-lamp microscope was used to examine the grade of the ACDs. Second, another ophthalmologist filmed the eyes using the SEC and two other ophthalmologists evaluated the grades on another day. The correlation and inter-rater reproducibility in total scores among the two devices were determined. Results: Total scores of clinical signs, evaluated by the two approaches, correlated significantly (both eyes: r = 0.918 (95% CI: 0.839 to 0.959; p < 0.001)), with substantial inter-rater agreement (weighted κ value = 0.631 (95% CI: 0.601 to 0.661; p < 0.001)). Conclusions: The SEC is as reliable as the conventional non-portable slit-lamp microscope for assessing ACDs.
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spelling pubmed-80024732021-03-28 Clinical Observation of Allergic Conjunctival Diseases with Portable and Recordable Slit-Lamp Device Yazu, Hiroyuki Shimizu, Eisuke Sato, Shinri Aketa, Naohiko Katayama, Taiichiro Yokoiwa, Ryota Sato, Yasunori Fukagawa, Kazumi Ogawa, Yoko Tsubota, Kazuo Fujishima, Hiroshi Diagnostics (Basel) Article Background: The incidence of allergic conjunctival diseases (ACDs) is gradually increasing worldwide. Both ophthalmologists and non-ophthalmologists prescribe eye drops to treat ACDs; however, there are many cases which are treated without sufficient examination and diagnosis of the eyes. We have invented a portable, recordable, and smartphone-attachable slit-lamp device—Smart Eye Camera (SEC). The purpose of this study was to compare the diagnostic abilities of ACDs between the SEC and the conventional, non-portable slit-lamp microscope. Methods: This prospective observational study included 32 eyes of 17 Japanese patients (mean age: 21.5 ± 14.8 years; range: 11–51 years; female: 5). The severity of 10 objective signs in the palpebral conjunctiva, bulbar conjunctiva, limbus, and cornea were scored on a grading scale of 0 to 4 (0 = normal; 1+ = mild; 2+ = moderate; 3+ = severe), respectively. First, the conventional slit-lamp microscope was used to examine the grade of the ACDs. Second, another ophthalmologist filmed the eyes using the SEC and two other ophthalmologists evaluated the grades on another day. The correlation and inter-rater reproducibility in total scores among the two devices were determined. Results: Total scores of clinical signs, evaluated by the two approaches, correlated significantly (both eyes: r = 0.918 (95% CI: 0.839 to 0.959; p < 0.001)), with substantial inter-rater agreement (weighted κ value = 0.631 (95% CI: 0.601 to 0.661; p < 0.001)). Conclusions: The SEC is as reliable as the conventional non-portable slit-lamp microscope for assessing ACDs. MDPI 2021-03-17 /pmc/articles/PMC8002473/ /pubmed/33802736 http://dx.doi.org/10.3390/diagnostics11030535 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ).
spellingShingle Article
Yazu, Hiroyuki
Shimizu, Eisuke
Sato, Shinri
Aketa, Naohiko
Katayama, Taiichiro
Yokoiwa, Ryota
Sato, Yasunori
Fukagawa, Kazumi
Ogawa, Yoko
Tsubota, Kazuo
Fujishima, Hiroshi
Clinical Observation of Allergic Conjunctival Diseases with Portable and Recordable Slit-Lamp Device
title Clinical Observation of Allergic Conjunctival Diseases with Portable and Recordable Slit-Lamp Device
title_full Clinical Observation of Allergic Conjunctival Diseases with Portable and Recordable Slit-Lamp Device
title_fullStr Clinical Observation of Allergic Conjunctival Diseases with Portable and Recordable Slit-Lamp Device
title_full_unstemmed Clinical Observation of Allergic Conjunctival Diseases with Portable and Recordable Slit-Lamp Device
title_short Clinical Observation of Allergic Conjunctival Diseases with Portable and Recordable Slit-Lamp Device
title_sort clinical observation of allergic conjunctival diseases with portable and recordable slit-lamp device
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8002473/
https://www.ncbi.nlm.nih.gov/pubmed/33802736
http://dx.doi.org/10.3390/diagnostics11030535
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