Cargando…

Effects of Low Dose Space Radiation Exposures on the Splenic Metabolome

Future space missions will include a return to the Moon and long duration deep space roundtrip missions to Mars. Leaving the protection that Low Earth Orbit provides will unavoidably expose astronauts to higher cumulative doses of space radiation, in addition to other stressors, e.g., microgravity....

Descripción completa

Detalles Bibliográficos
Autores principales:	Laiakis, Evagelia C., Shuryak, Igor, Deziel, Annabella, Wang, Yi-Wen, Barnette, Brooke L., Yu, Yongjia, Ullrich, Robert L., Fornace, Albert J., Emmett, Mark R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8002539/ https://www.ncbi.nlm.nih.gov/pubmed/33802822 http://dx.doi.org/10.3390/ijms22063070

Ejemplares similares

Mitochondrial Effects in the Liver of C57BL/6 Mice by Low Dose, High Energy, High Charge Irradiation
por: Barnette, Brooke L., et al.
Publicado: (2021)

Biofluid Metabolomics and Lipidomics of Mice Exposed to External Very High-Dose Rate Radiation
por: Pannkuk, Evan L., et al.
Publicado: (2022)

Serum Metabolomic Alterations Associated with Cesium-137 Internal Emitter Delivered in Various Dose Rates
por: Li, Heng-Hong, et al.
Publicado: (2020)

Lipidomic Signatures of Nonhuman Primates with Radiation-Induced Hematopoietic Syndrome
por: Pannkuk, Evan L., et al.
Publicado: (2017)

Author Correction: Lipidomic Signatures of Nonhuman Primates with Radiation-Induced Hematopoietic Syndrome
por: Pannkuk, Evan L., et al.
Publicado: (2019)

Impact of inflammatory signaling on radiation biodosimetry: mouse model of inflammatory bowel disease
por: Mukherjee, Sanjay, et al.
Publicado: (2019)

Metabolomic Analysis in Severe Childhood Pneumonia in The Gambia, West Africa: Findings from a Pilot Study
por: Laiakis, Evagelia C., et al.
Publicado: (2010)

Addition of metabolomics to the omics spectrum for cancer biomarker development– demonstration with the KrasG12D mouse model for pancreatic carcinoma
por: Laiakis, Evagelia C, et al.
Publicado: (2014)

Effects of Genetic Variation on Urinary Small Molecule Signatures of Mice after Exposure to Ionizing Radiation: A Study of p53 Deficiency
por: Pannkuk, Evan L., et al.
Publicado: (2020)

Temporal Effects on Radiation Responses in Nonhuman Primates: Identification of Biofluid Small Molecule Signatures by Gas Chromatography–Mass Spectrometry Metabolomics
por: Pannkuk, Evan L., et al.
Publicado: (2019)

Quantitative proteomic analytic approaches to identify metabolic changes in the medial prefrontal cortex of rats exposed to space radiation
por: Laiakis, Evagelia C., et al.
Publicado: (2022)

Metabolic Phenotyping Reveals a Lipid Mediator Response to Ionizing Radiation
por: Laiakis, Evagelia C., et al.
Publicado: (2014)

Biomarker integration for improved biodosimetry of mixed neutron + photon exposures
por: Shuryak, Igor, et al.
Publicado: (2023)

Distinct serum metabolomics profiles associated with malignant progression in the Kras(G12D) mouse model of pancreatic ductal adenocarcinoma
por: LaConti, Joseph J, et al.
Publicado: (2015)

Serum lipidomic analysis from mixed neutron/X-ray radiation fields reveals a hyperlipidemic and pro-inflammatory phenotype
por: Laiakis, Evagelia C., et al.
Publicado: (2019)

Mechanistic Modeling of Dose and Dose Rate Dependences of Radiation-Induced DNA Double Strand Break Rejoining Kinetics in Saccharomyces cerevisiae
por: Shuryak, Igor
Publicado: (2016)

Radiation-Induced Carcinogenesis: Mechanistically Based Differences between Gamma-Rays and Neutrons, and Interactions with DMBA
por: Shuryak, Igor, et al.
Publicado: (2011)

Comparative RNA-Seq transcriptome analyses reveal dynamic time-dependent effects of (56)Fe, (16)O, and (28)Si irradiation on the induction of murine hepatocellular carcinoma
por: Nia, Anna M., et al.
Publicado: (2020)

Hepatic lipid signatures of little brown bats (Myotis lucifugus) and big brown bats (Eptesicus fuscus) at early stages of white-nose syndrome
por: Pannkuk, Evan L., et al.
Publicado: (2021)

Efficient identification of multiple pathways: RNA-Seq analysis of livers from (56)Fe ion irradiated mice
por: Nia, Anna M., et al.
Publicado: (2020)

Quantitative modeling of responses to chronic ionizing radiation exposure using targeted and non-targeted effects
por: Shuryak, Igor
Publicado: (2017)

Long-Term Differential Changes in Mouse Intestinal Metabolomics after γ and Heavy Ion Radiation Exposure
por: Cheema, Amrita K., et al.
Publicado: (2014)

Quantitative modeling of carcinogenesis induced by single beams or mixtures of space radiations using targeted and non-targeted effects
por: Shuryak, Igor, et al.
Publicado: (2021)

Space radiation exposure persistently increased leptin and IGF1 in serum and activated leptin-IGF1 signaling axis in mouse intestine
por: Suman, Shubhankar, et al.
Publicado: (2016)

Quantitative Metabolomic Analysis of Urinary Citrulline and Calcitroic Acid in Mice after Exposure to Various Types of Ionizing Radiation
por: Goudarzi, Maryam, et al.
Publicado: (2016)

A practical approach for continuous in situ characterization of radiation quality factors in space
por: Shuryak, Igor, et al.
Publicado: (2022)

Modeling space radiation induced cognitive dysfunction using targeted and non-targeted effects
por: Shuryak, Igor, et al.
Publicado: (2021)

Space radiation triggers persistent stress response, increases senescent signaling, and decreases cell migration in mouse intestine
por: Kumar, Santosh, et al.
Publicado: (2018)

Cytogenetically-based biodosimetry after high doses of radiation
por: Pujol-Canadell, Monica, et al.
Publicado: (2020)

New Approaches for Quantitative Reconstruction of Radiation Dose in Human Blood Cells
por: Ghandhi, Shanaz A., et al.
Publicado: (2019)

Therapeutic and space radiation exposure of mouse brain causes impaired DNA repair response and premature senescence by chronic oxidant production
por: Suman, Shubhankar, et al.
Publicado: (2013)

VADER: a variable dose-rate external (137)Cs irradiator for internal emitter and low dose rate studies
por: Garty, Guy, et al.
Publicado: (2020)

Space-type radiation induces multimodal responses in the mouse gut microbiome and metabolome
por: Casero, David, et al.
Publicado: (2017)

Inactivation Rates for Airborne Human Coronavirus by Low Doses of 222 nm Far-UVC Radiation
por: Welch, David, et al.
Publicado: (2022)

Quantitative modeling of multigenerational effects of chronic ionizing radiation using targeted and nontargeted effects
por: Shuryak, Igor, et al.
Publicado: (2021)

Expression of Stem Cell Markers in High-LET Space Radiation-Induced Intestinal Tumors in Apc(1638N/+) Mouse Intestine
por: Kwiatkowski, Elaina, et al.
Publicado: (2023)

Exposure to Heavy Ion Radiation Induces Persistent Oxidative Stress in Mouse Intestine
por: Datta, Kamal, et al.
Publicado: (2012)

Considerations for practical dose equivalent assessment of space radiation and exposure risk reduction in deep space
por: Naito, Masayuki, et al.
Publicado: (2022)

Heavy Ion Radiation Exposure Triggered Higher Intestinal Tumor Frequency and Greater β-Catenin Activation than γ Radiation in APC(Min/+) Mice
por: Datta, Kamal, et al.
Publicado: (2013)

Cross-platform validation of a mouse blood gene signature for quantitative reconstruction of radiation dose
por: Ghandhi, Shanaz A., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_biu322itmu62rsj1cae8fpldlh