Cargando…

Breakthrough Mucormycosis Developing on Mucorales-Active Antifungals Portrays a Poor Prognosis in Patients with Hematologic Cancer

Although breakthrough mucormycosis (BT-MCR) is known to develop on mold-active antifungals without Mucorales activity, it can also occur while on Mucorales-active antifungals. Herein, we retrospectively compared the characteristics and outcomes of patients with hematologic malignancies (HMs) or hema...

Descripción completa

Detalles Bibliográficos
Autores principales:	Axell-House, Dierdre B., Wurster, Sebastian, Jiang, Ying, Kyvernitakis, Andreas, Lewis, Russell E., Tarrand, Jeffrey J., Raad, Issam I., Kontoyiannis, Dimitrios P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8002622/ https://www.ncbi.nlm.nih.gov/pubmed/33802827 http://dx.doi.org/10.3390/jof7030217

Ejemplares similares

255. Breakthrough Mucormycosis (BT-MCR) on Antifungals Having Mucorales Activity Portrays Worse Prognosis compared with BT-MCR on Mold-Active Antifungals with no Mucorales Activity
por: Axell-House, Dierdre B, et al.
Publicado: (2019)

Impact of Hyperglycemia and Diabetes Mellitus on Breakthrough Mucormycosis Outcomes in Patients with Hematologic Malignancies—Complex and Intriguing Associations
por: Franklin, Alexander, et al.
Publicado: (2022)

2102. Common co-occurence in the respiratory tract of Mucorales with Gram-negative rods in patients with hematologic malignancy and sinopulmonary mucormycosis
por: Egge, Stephanie L, et al.
Publicado: (2022)

710. Comparison of Initial CXR to CT in Patients (pts) with Hematologic Malignancy (HEM) and Documented Symptomatic Pulmonary Mucormycosis (PM)
por: Franklin, Alexander, et al.
Publicado: (2021)

848. Discordant Chest Radiography and Computed Tomography Findings in Patients with Hematologic Malignancy and Invasive Mucormycosis: What Are the Prognostic Implications?
por: Wurster, Sebastian, et al.
Publicado: (2023)

Taking a Closer Look: Clinical and Histopathological Characteristics of Culture-Positive versus Culture-Negative Pulmonary Mucormycosis
por: Spallone, Amy, et al.
Publicado: (2022)

Special Issue: Mucorales and Mucormycosis
por: Dannaoui, Eric, et al.
Publicado: (2019)

828. Do lung co-infections influence outcome in patients with hematological malignancies and culture-documented invasive pulmonary aspergillosis?
por: Matsuo, Takahiro, et al.
Publicado: (2023)

Mucorales and Mucormycosis: Recent Insights and Future Prospects
por: Tahiri, Ghizlane, et al.
Publicado: (2023)

Genetic Manipulation in Mucorales and New Developments to Study Mucormycosis
por: Lax, Carlos, et al.
Publicado: (2022)

380. Drosophila melanogaster as a Facile Model for Large-Scale Studies of Virulence Mechanisms and Antifungal Drug Efficacy in Candida auris Candidiasis
por: Bandi, Ashwini, et al.
Publicado: (2018)

Blockade of the PD-1/PD-L1 Immune Checkpoint Pathway Improves Infection Outcomes and Enhances Fungicidal Host Defense in a Murine Model of Invasive Pulmonary Mucormycosis
por: Wurster, Sebastian, et al.
Publicado: (2022)

Mucorales-Specific T Cells in Patients with Hematologic Malignancies
por: Potenza, Leonardo, et al.
Publicado: (2016)

PCR-based Diagnosis of Mucormycosis Targeting Mucorales-specific Genes
por: Baldin, Clara, et al.
Publicado: (2017)

Antifungal-resistant Mucorales in different indoor environments
por: Caetano, Liliana Aranha, et al.
Publicado: (2018)

In Vitro and In Vivo Evaluation of Voriconazole-Containing Antifungal Combinations against Mucorales Using a Galleria mellonella Model of Mucormycosis
por: Macedo, Daiana, et al.
Publicado: (2019)

1725. Shear Forces Induce a Transient, Calcineurin-Dependent Hyper-Virulent Phenotype in Mucorales via Soluble Factors
por: Wurster, Sebastian, et al.
Publicado: (2019)

827. Adjunct terbinafine in patients with leukemia and invasive fusariosis with skin lesions: Discordance between responses of skin lesions and systemic outcomes
por: Matsuo, Takahiro, et al.
Publicado: (2023)

2589. Legionella pneumonia in cancer patients: 12-year experience at MD Anderson Cancer Center 2009-2021
por: Matsuo, Takahiro, et al.
Publicado: (2023)

Tornadic Shear Stress Induces a Transient, Calcineurin-Dependent Hypervirulent Phenotype in Mucorales Molds
por: Wurster, Sebastian, et al.
Publicado: (2020)

457 Actinomyces Infection in Hematologic and Solid Cancer Patients at the University of Texas MD Anderson Cancer Center in 1998-2014
por: Gutierrez, Andres, et al.
Publicado: (2014)

Clinical Approach to Evaluation of Underlying Cardiac Device Infection in Patients Hospitalized with Bacteremia
por: Axell-House, Dierdre B., et al.
Publicado: (2023)

Blood Mucorales PCR to track down Aspergillus and Mucorales co-infections in at-risk hematology patients: A case-control study
por: Aerts, Robina, et al.
Publicado: (2022)

2038. Invasive Mucormycosis Management: Mucorales PCR Provides Important, Novel Diagnostic Information
por: Wilgers, Kyle, et al.
Publicado: (2018)

Serial Detection of Circulating Mucorales DNA in Invasive Mucormycosis: A Retrospective Multicenter Evaluation
por: Mercier, Toine, et al.
Publicado: (2019)

Evaluation of environmental Mucorales contamination in and around the residence of COVID-19-associated mucormycosis patients
por: Ghosh, Anup K., et al.
Publicado: (2022)

359. Baseline Serum Aspergillus Galactomannan Index Among Aspergillus Species in Hematologic Malignancies Patients With Invasive Pulmonary Aspergillosis
por: Magira, Eleni, et al.
Publicado: (2018)

Role of the Non-Canonical RNAi Pathway in the Antifungal Resistance and Virulence of Mucorales
por: Cánovas-Márquez, José Tomás, et al.
Publicado: (2021)

Antifungal activity of Taurolidine against Mucorales: An in vitro study on clinical isolates
por: Jafarian, Hadis, et al.
Publicado: (2022)

An Antimicrobial Peptidomimetic Induces Mucorales Cell Death through Mitochondria-Mediated Apoptosis
por: Barbu, E. Magda, et al.
Publicado: (2013)

Outcomes in Invasive Pulmonary Aspergillosis Infections Complicated by Respiratory Viral Infections in Patients With Hematologic Malignancies: A Case-Control Study
por: Magira, Eleni E, et al.
Publicado: (2019)

Corrigendum: Outcomes in Invasive Pulmonary Aspergillosis Infections Complicated by Respiratory Viral Infections in Patients With Hematologic Malignancies: A Case-Control Study
por: Magira, Eleni E, et al.
Publicado: (2019)

Therapy of Mucormycosis
por: Sipsas, Nikolaos V., et al.
Publicado: (2018)

Mucormycosis of the Central Nervous System
por: Chikley, Amanda, et al.
Publicado: (2019)

356. Bronchoalveolar Lavage Fluid Cytology by GMS Stain for the Diagnosis of Invasive Pulmonary Aspergillosis in Patients With Hematologic Malignancies: Analysis of 67 Episodes
por: Fernández-Cruz, Ana, et al.
Publicado: (2018)

Mucormycosis in 2023: an update on pathogenesis and management
por: Alqarihi, Abdullah, et al.
Publicado: (2023)

Mucorales/Fusarium Mixed Infection in Hematologic Patient with COVID-19 Complications: An Unfortunate Combination
por: Marino, Andrea, et al.
Publicado: (2023)

Mucorales Species and Macrophages
por: Nicolás, Francisco E., et al.
Publicado: (2020)

Mixed Mycobacterium Avium-Intracellulare and Serratia Marcescens Cellulitis of the Breast in an HIV-Negative Patient with Breast Cancer: A Case Report
por: Kyvernitakis, Andreas, et al.
Publicado: (2016)

2114. Invasive fusariosis in the era of mold active azoles and molecular targeted chemotherapy: Increasing incidence and lack of improved outcomes
por: Matsuo, Takahiro, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_6jv3v2stnnc9lvtdrs5fv1mtug