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Recent Updates on the Significance of KRAS Mutations in Colorectal Cancer Biology

The most commonly mutated isoform of RAS among all cancer subtypes is KRAS. In this review, we focus on the special role of KRAS mutations in colorectal cancer (CRC), aiming to collect recent data on KRAS-driven enhanced cell signalling, in vitro and in vivo research models, and CRC development-rela...

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Detalles Bibliográficos
Autores principales:	László, Loretta, Kurilla, Anita, Takács, Tamás, Kudlik, Gyöngyi, Koprivanacz, Kitti, Buday, László, Vas, Virag
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8002639/ https://www.ncbi.nlm.nih.gov/pubmed/33802849 http://dx.doi.org/10.3390/cells10030667

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