Cargando…

The Role of TRPA1 in Skin Physiology and Pathology

The transient receptor potential ankyrin 1 (TRPA1), a member of the TRP superfamily of channels, acts as ‘polymodal cellular sensor’ on primary sensory neurons where it mediates the peripheral and central processing of pain, itch, and thermal sensation. However, the TRPA1 expression extends far beyo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Maglie, Roberto, Souza Monteiro de Araujo, Daniel, Antiga, Emiliano, Geppetti, Pierangelo, Nassini, Romina, De Logu, Francesco
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8002674/ https://www.ncbi.nlm.nih.gov/pubmed/33802836 http://dx.doi.org/10.3390/ijms22063065

Ejemplares similares

TRPA1 as a therapeutic target for nociceptive pain
por: Souza Monteiro de Araujo, Daniel, et al.
Publicado: (2020)

TRPA1 Role in Inflammatory Disorders: What Is Known So Far?
por: Landini, Lorenzo, et al.
Publicado: (2022)

Acetaldehyde via CGRP receptor and TRPA1 in Schwann cells mediates ethanol-evoked periorbital mechanical allodynia in mice: relevance for migraine
por: Landini, Lorenzo, et al.
Publicado: (2023)

Neuropathic-like Nociception and Spinal Cord Neuroinflammation Are Dependent on the TRPA1 Channel in Multiple Sclerosis Models in Mice
por: Dalenogare, Diéssica Padilha, et al.
Publicado: (2023)

The TRPA1 Channel Amplifies the Oxidative Stress Signal in Melanoma
por: De Logu, Francesco, et al.
Publicado: (2021)

TRP Channels in Cancer: Signaling Mechanisms and Translational Approaches
por: Marini, Matilde, et al.
Publicado: (2023)

TRPA1 mediates damage of the retina induced by ischemia and reperfusion in mice
por: Souza Monteiro de Araújo, Daniel, et al.
Publicado: (2020)

Oxidative stress mediates thalidomide-induced pain by targeting peripheral TRPA1 and central TRPV4
por: De Logu, Francesco, et al.
Publicado: (2020)

TRPA1 mediates the antinociceptive properties of the constituent of Crocus sativus L., safranal
por: Li Puma, Simone, et al.
Publicado: (2019)

Schwann cell TRPA1 mediates neuroinflammation that sustains macrophage-dependent neuropathic pain in mice
por: De Logu, Francesco, et al.
Publicado: (2017)

TRPA1/NOX in the soma of trigeminal ganglion neurons mediates migraine-related pain of glyceryl trinitrate in mice
por: Marone, Ilaria Maddalena, et al.
Publicado: (2018)

Steroidal and non-steroidal third-generation aromatase inhibitors induce pain-like symptoms via TRPA1
por: Fusi, Camilla, et al.
Publicado: (2014)

Migraine-provoking substances evoke periorbital allodynia in mice
por: De Logu, Francesco, et al.
Publicado: (2019)

Transient receptor potential ankyrin 1 (TRPA1) plays a critical role in a mouse model of cancer pain
por: Antoniazzi, Caren Tatiane De David, et al.
Publicado: (2018)

Periorbital Nociception in a Progressive Multiple Sclerosis Mouse Model Is Dependent on TRPA1 Channel Activation
por: Dalenogare, Diéssica Padilha, et al.
Publicado: (2021)

TRPA1 Expression in Synovial Sarcoma May Support Neural Origin
por: De Logu, Francesco, et al.
Publicado: (2020)

TRPA1 and other TRP channels in migraine
por: Benemei, Silvia, et al.
Publicado: (2013)

Transient receptor potential ankyrin 1 contributes to somatic pain hypersensitivity in experimental colitis
por: Jain, Piyush, et al.
Publicado: (2020)

β2-and β3-Adrenergic Receptors Contribute to Cancer-Evoked Pain in a Mouse Model of Osteosarcoma via Modulation of Neural Macrophages
por: Bruno, Gennaro, et al.
Publicado: (2021)

Retinal Toxicity Induced by Chemical Agents
por: Souza Monteiro de Araújo, Daniel, et al.
Publicado: (2022)

Schwann cell endosome CGRP signals elicit periorbital mechanical allodynia in mice
por: De Logu, Francesco, et al.
Publicado: (2022)

A Fast and Automated Melanin-bleaching Method for Histopathologic Evaluation of Pigmented Melanoma Tissues
por: Ugolini, Filippo, et al.
Publicado: (2022)

Recognition of Cutaneous Melanoma on Digitized Histopathological Slides via Artificial Intelligence Algorithm
por: De Logu, Francesco, et al.
Publicado: (2020)

The cytokine milieu of bullous pemphigoid: Current and novel therapeutic targets
por: Maglie, Roberto, et al.
Publicado: (2023)

Dermatitis Herpetiformis: Novel Perspectives
por: Antiga, Emiliano, et al.
Publicado: (2019)

Localized pemphigus exacerbation associated with underlying breast cancer
por: Maglie, Roberto, et al.
Publicado: (2020)

CGRP receptors and TRP channels in migraine
por: Geppetti, Pierangelo, et al.
Publicado: (2015)

Emerging Pharmacological Treatments for Migraine in the Pediatric Population
por: Iannone, Luigi Francesco, et al.
Publicado: (2022)

Sweet Syndrome Following SARS-CoV2 Vaccination
por: Baffa, Maria Efenesia, et al.
Publicado: (2021)

Inverted‐U serration pattern: a novel clue for the diagnosis of anti‐laminin‐γ1 pemphigoid
por: Senatore, Stefano, et al.
Publicado: (2021)

Digital Quantification of Intratumoral CD8+ T-Cells Predicts Relapse and Unfavorable Outcome in Uveal Melanoma
por: Hurdogan, Ozge, et al.
Publicado: (2022)

Granular Deposits of IgA in the Skin of Coeliac Patients Without Dermatitis Herpetiformis: A Prospective Multicentric Analysis
por: ANTIGA, Emiliano, et al.
Publicado: (2021)

Protocol and methods for testing the efficacy of well-being therapy in chronic migraine patients: a randomized controlled trial
por: Mansueto, Giovanni, et al.
Publicado: (2018)

COVID-19 pneumonia during long-term migraine prophylaxis with fremanezumab: a case report
por: Iannone, Luigi Francesco, et al.
Publicado: (2021)

Immune-Mediated Dermatoses in Patients with Haematological Malignancies: A Comprehensive Review
por: Maglie, Roberto, et al.
Publicado: (2020)

P010. OnabotulinumtoxinA for treatment of chronic migraine: results after 1 year of treatment
por: Rossi, Eleonora, et al.
Publicado: (2015)

Anatomy, Physiology, and Pathology of the Skin
Publicado: (1825)

Inflammation—the role of TRPA1 channel
por: Yao, Kaifang, et al.
Publicado: (2023)

The role of TRPA1 channels in thermosensation
por: Zhang, Hao, et al.
Publicado: (2022)

Digital Immunophenotyping Predicts Disease Free and Overall Survival in Early Stage Melanoma Patients
por: De Logu, Francesco, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_km9gft2eovm3p7icje06dovml8