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Pyrrole–Aminopyrimidine Ensembles: Cycloaddition of Guanidine to Acylethynylpyrroles

An efficient method for the synthesis of pharmaceutically prospective pyrrole–aminopyrimidine ensembles (in up to 91% yield) by the cyclocondensation of easily available acylethynylpyrroles with guanidine nitrate has been developed. The reaction proceeds under heating (110–115 °C, 4 h) in the KOH/DM...

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Detalles Bibliográficos
Autores principales:	Petrova, Olga V., Budaev, Arsalan B., Sagitova, Elena F., Ushakov, Igor A., Sobenina, Lyubov N., Ivanov, Andrey V., Trofimov, Boris A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8002744/ https://www.ncbi.nlm.nih.gov/pubmed/33803018 http://dx.doi.org/10.3390/molecules26061692

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