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Epigenetic Treatment of Urothelial Carcinoma Cells Sensitizes to Cisplatin Chemotherapy and PARP Inhibitor Treatment
SIMPLE SUMMARY: Muscle-invasive urothelial carcinoma of the bladder (UC) is treated with chemotherapies based on the DNA-damaging drug cisplatin, which only works temporarily due to the development of drug resistance. In this study, we show that it may be possible to overcome such resistances by tre...
Autores principales: | Thy, Sophia, Hommel, Alexandra, Meneceur, Sarah, Bartkowiak, Anna L., Schulz, Wolfgang A., Niegisch, Günter, Hoffmann, Michèle J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8002916/ https://www.ncbi.nlm.nih.gov/pubmed/33803654 http://dx.doi.org/10.3390/cancers13061376 |
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