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Seasonal Differences in Cyclospora cayetanensis Prevalence in Colombian Indigenous People
Fecal-orally transmitted cyclosporiasis is frequent in remote resource-limited settings in Central and South America with poor hygiene conditions. In this study, we aimed at assessing seasonal effects on the epidemiology of colonization or infection with C. cayetanensis in Colombian indigenous peopl...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8002917/ https://www.ncbi.nlm.nih.gov/pubmed/33803496 http://dx.doi.org/10.3390/microorganisms9030627 |
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author | Frickmann, Hagen Alker, Juliane Hansen, Jessica Dib, Juan Carlos Aristizabal, Andrés Concha, Gustavo Schotte, Ulrich Kann, Simone |
author_facet | Frickmann, Hagen Alker, Juliane Hansen, Jessica Dib, Juan Carlos Aristizabal, Andrés Concha, Gustavo Schotte, Ulrich Kann, Simone |
author_sort | Frickmann, Hagen |
collection | PubMed |
description | Fecal-orally transmitted cyclosporiasis is frequent in remote resource-limited settings in Central and South America with poor hygiene conditions. In this study, we aimed at assessing seasonal effects on the epidemiology of colonization or infection with C. cayetanensis in Colombian indigenous people living under very restricted conditions. In the rainy season between July and November and in the dry season between January and April, stool samples from indigenous people with and without gastrointestinal symptoms were collected and screened for C. cayetanensis applying in-house real-time polymerase chain reaction (PCR). In the rainy season and in the dry season, positive PCR results were observed for 11.8% (16/136) and 5.1% (15/292), respectively, with cycle threshold (Ct) values of 30.6 (±3.4) and 34.4 (±1.6), respectively. Despite higher parasite loads in the rainy season, fewer individuals (2/16, 12.5%) reported gastrointestinal symptoms compared to the dry season (6/15, 40%). In conclusion, considerable prevalence of C. cayetanensis in Colombian indigenous people persists in the dry season. Low proportions of gastrointestinal symptoms along with higher parasite loads make colonization likely rather than infection. |
format | Online Article Text |
id | pubmed-8002917 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-80029172021-03-28 Seasonal Differences in Cyclospora cayetanensis Prevalence in Colombian Indigenous People Frickmann, Hagen Alker, Juliane Hansen, Jessica Dib, Juan Carlos Aristizabal, Andrés Concha, Gustavo Schotte, Ulrich Kann, Simone Microorganisms Communication Fecal-orally transmitted cyclosporiasis is frequent in remote resource-limited settings in Central and South America with poor hygiene conditions. In this study, we aimed at assessing seasonal effects on the epidemiology of colonization or infection with C. cayetanensis in Colombian indigenous people living under very restricted conditions. In the rainy season between July and November and in the dry season between January and April, stool samples from indigenous people with and without gastrointestinal symptoms were collected and screened for C. cayetanensis applying in-house real-time polymerase chain reaction (PCR). In the rainy season and in the dry season, positive PCR results were observed for 11.8% (16/136) and 5.1% (15/292), respectively, with cycle threshold (Ct) values of 30.6 (±3.4) and 34.4 (±1.6), respectively. Despite higher parasite loads in the rainy season, fewer individuals (2/16, 12.5%) reported gastrointestinal symptoms compared to the dry season (6/15, 40%). In conclusion, considerable prevalence of C. cayetanensis in Colombian indigenous people persists in the dry season. Low proportions of gastrointestinal symptoms along with higher parasite loads make colonization likely rather than infection. MDPI 2021-03-18 /pmc/articles/PMC8002917/ /pubmed/33803496 http://dx.doi.org/10.3390/microorganisms9030627 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ). |
spellingShingle | Communication Frickmann, Hagen Alker, Juliane Hansen, Jessica Dib, Juan Carlos Aristizabal, Andrés Concha, Gustavo Schotte, Ulrich Kann, Simone Seasonal Differences in Cyclospora cayetanensis Prevalence in Colombian Indigenous People |
title | Seasonal Differences in Cyclospora cayetanensis Prevalence in Colombian Indigenous People |
title_full | Seasonal Differences in Cyclospora cayetanensis Prevalence in Colombian Indigenous People |
title_fullStr | Seasonal Differences in Cyclospora cayetanensis Prevalence in Colombian Indigenous People |
title_full_unstemmed | Seasonal Differences in Cyclospora cayetanensis Prevalence in Colombian Indigenous People |
title_short | Seasonal Differences in Cyclospora cayetanensis Prevalence in Colombian Indigenous People |
title_sort | seasonal differences in cyclospora cayetanensis prevalence in colombian indigenous people |
topic | Communication |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8002917/ https://www.ncbi.nlm.nih.gov/pubmed/33803496 http://dx.doi.org/10.3390/microorganisms9030627 |
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