Cargando…
The Impact of the Nephrotoxin Ochratoxin A on Human Renal Cells Studied by a Novel Co-Culture Model Is Influenced by the Presence of Fibroblasts
The kidney is threatened by a lot of potentially toxic substances. To study the influence of the nephrotoxin ochratoxin A (OTA) we established a cell co-culture model consisting of human renal proximal tubule cells and fibroblasts. We studied the effect of OTA on cell survival, the expression of gen...
Autores principales: | Schwerdt, Gerald, Kopf, Michael, Gekle, Michael |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003035/ https://www.ncbi.nlm.nih.gov/pubmed/33803529 http://dx.doi.org/10.3390/toxins13030219 |
Ejemplares similares
-
The nephrotoxin ochratoxin a impairs resilience of energy homeostasis of human proximal tubule cells
por: Schwerdt, Gerald, et al.
Publicado: (2023) -
Acidosis Activates the Nrf2 Pathway in Renal Proximal Tubule-Derived Cells through a Crosstalk with Renal Fibroblasts
por: Schulz, Marie-Christin, et al.
Publicado: (2023) -
Contribution of Organ Vasculature in Rat Renal Analysis for Ochratoxin A: Relevance to Toxicology of Nephrotoxins
por: Mantle, Peter, et al.
Publicado: (2015) -
Acute renal failure caused by nephrotoxins.
por: Oken, D E
Publicado: (1976) -
Weighted Correlation Network Analysis Reveals CDK2 as a Regulator of a Ubiquitous Environmental Toxin-Induced Cell-Cycle Arrest
por: Dubourg, Virginie, et al.
Publicado: (2020)