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Shiga Toxins: An Update on Host Factors and Biomedical Applications

Shiga toxins (Stxs) are classic bacterial toxins and major virulence factors of toxigenic Shigella dysenteriae and enterohemorrhagic Escherichia coli (EHEC). These toxins recognize a glycosphingolipid globotriaosylceramide (Gb3/CD77) as their receptor and inhibit protein synthesis in cells by cleavi...

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Detalles Bibliográficos
Autores principales: Liu, Yang, Tian, Songhai, Thaker, Hatim, Dong, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003205/
https://www.ncbi.nlm.nih.gov/pubmed/33803852
http://dx.doi.org/10.3390/toxins13030222