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Synthesis, Antifungal Activity, and 3D-QSAR Study of Novel Nopol-Derived 1,3,4-Thiadiazole-Thiourea Compounds
A series of novel nopol derivatives bearing the 1,3,4-thiadiazole-thiourea moiety were designed and synthesized by multi-step reactions in search of potent natural product-based antifungal agents. Their structures were confirmed by FT-IR, NMR, ESI-MS, and elemental analysis. Antifungal activity of t...
Autores principales: | Chen, Ming, Duan, Wen-Gui, Lin, Gui-Shan, Fan, Zhong-Tian, Wang, Xiu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003325/ https://www.ncbi.nlm.nih.gov/pubmed/33803890 http://dx.doi.org/10.3390/molecules26061708 |
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