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Mitochondrial DNA Profiles of Individuals from a 12th Century Necropolis in Feldioara (Transylvania)
The genetic signature of modern Europeans is the cumulated result of millennia of discrete small-scale exchanges between multiple distinct population groups that performed a repeated cycle of movement, settlement, and interactions with each other. In this study we aimed to highlight one such minute...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003334/ https://www.ncbi.nlm.nih.gov/pubmed/33808521 http://dx.doi.org/10.3390/genes12030436 |
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author | Gînguță, Alexandra Rusu, Ioana Mircea, Cristina Ioniță, Adrian Banciu, Horia L. Kelemen, Beatrice |
author_facet | Gînguță, Alexandra Rusu, Ioana Mircea, Cristina Ioniță, Adrian Banciu, Horia L. Kelemen, Beatrice |
author_sort | Gînguță, Alexandra |
collection | PubMed |
description | The genetic signature of modern Europeans is the cumulated result of millennia of discrete small-scale exchanges between multiple distinct population groups that performed a repeated cycle of movement, settlement, and interactions with each other. In this study we aimed to highlight one such minute genetic cycle in a sea of genetic interactions by reconstructing part of the genetic story of the migration, settlement, interaction, and legacy of what is today the Transylvanian Saxon. The analysis of the mitochondrial DNA control region of 13 medieval individuals from Feldioara necropolis (Transylvania region, Romania) reveals a genetically heterogeneous group where all identified haplotypes are different. Most of the perceived maternal lineages are of Western Eurasian origin, except for the Central Asiatic haplogroup C seen in only one sample. Comparisons with historical and modern populations describe the contribution of the investigated Saxon settlers to the genetic history of this part of Europe. |
format | Online Article Text |
id | pubmed-8003334 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-80033342021-03-28 Mitochondrial DNA Profiles of Individuals from a 12th Century Necropolis in Feldioara (Transylvania) Gînguță, Alexandra Rusu, Ioana Mircea, Cristina Ioniță, Adrian Banciu, Horia L. Kelemen, Beatrice Genes (Basel) Article The genetic signature of modern Europeans is the cumulated result of millennia of discrete small-scale exchanges between multiple distinct population groups that performed a repeated cycle of movement, settlement, and interactions with each other. In this study we aimed to highlight one such minute genetic cycle in a sea of genetic interactions by reconstructing part of the genetic story of the migration, settlement, interaction, and legacy of what is today the Transylvanian Saxon. The analysis of the mitochondrial DNA control region of 13 medieval individuals from Feldioara necropolis (Transylvania region, Romania) reveals a genetically heterogeneous group where all identified haplotypes are different. Most of the perceived maternal lineages are of Western Eurasian origin, except for the Central Asiatic haplogroup C seen in only one sample. Comparisons with historical and modern populations describe the contribution of the investigated Saxon settlers to the genetic history of this part of Europe. MDPI 2021-03-19 /pmc/articles/PMC8003334/ /pubmed/33808521 http://dx.doi.org/10.3390/genes12030436 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ). |
spellingShingle | Article Gînguță, Alexandra Rusu, Ioana Mircea, Cristina Ioniță, Adrian Banciu, Horia L. Kelemen, Beatrice Mitochondrial DNA Profiles of Individuals from a 12th Century Necropolis in Feldioara (Transylvania) |
title | Mitochondrial DNA Profiles of Individuals from a 12th Century Necropolis in Feldioara (Transylvania) |
title_full | Mitochondrial DNA Profiles of Individuals from a 12th Century Necropolis in Feldioara (Transylvania) |
title_fullStr | Mitochondrial DNA Profiles of Individuals from a 12th Century Necropolis in Feldioara (Transylvania) |
title_full_unstemmed | Mitochondrial DNA Profiles of Individuals from a 12th Century Necropolis in Feldioara (Transylvania) |
title_short | Mitochondrial DNA Profiles of Individuals from a 12th Century Necropolis in Feldioara (Transylvania) |
title_sort | mitochondrial dna profiles of individuals from a 12th century necropolis in feldioara (transylvania) |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003334/ https://www.ncbi.nlm.nih.gov/pubmed/33808521 http://dx.doi.org/10.3390/genes12030436 |
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