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Mitochondrial DNA Profiles of Individuals from a 12th Century Necropolis in Feldioara (Transylvania)

The genetic signature of modern Europeans is the cumulated result of millennia of discrete small-scale exchanges between multiple distinct population groups that performed a repeated cycle of movement, settlement, and interactions with each other. In this study we aimed to highlight one such minute...

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Autores principales: Gînguță, Alexandra, Rusu, Ioana, Mircea, Cristina, Ioniță, Adrian, Banciu, Horia L., Kelemen, Beatrice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003334/
https://www.ncbi.nlm.nih.gov/pubmed/33808521
http://dx.doi.org/10.3390/genes12030436
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author Gînguță, Alexandra
Rusu, Ioana
Mircea, Cristina
Ioniță, Adrian
Banciu, Horia L.
Kelemen, Beatrice
author_facet Gînguță, Alexandra
Rusu, Ioana
Mircea, Cristina
Ioniță, Adrian
Banciu, Horia L.
Kelemen, Beatrice
author_sort Gînguță, Alexandra
collection PubMed
description The genetic signature of modern Europeans is the cumulated result of millennia of discrete small-scale exchanges between multiple distinct population groups that performed a repeated cycle of movement, settlement, and interactions with each other. In this study we aimed to highlight one such minute genetic cycle in a sea of genetic interactions by reconstructing part of the genetic story of the migration, settlement, interaction, and legacy of what is today the Transylvanian Saxon. The analysis of the mitochondrial DNA control region of 13 medieval individuals from Feldioara necropolis (Transylvania region, Romania) reveals a genetically heterogeneous group where all identified haplotypes are different. Most of the perceived maternal lineages are of Western Eurasian origin, except for the Central Asiatic haplogroup C seen in only one sample. Comparisons with historical and modern populations describe the contribution of the investigated Saxon settlers to the genetic history of this part of Europe.
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spelling pubmed-80033342021-03-28 Mitochondrial DNA Profiles of Individuals from a 12th Century Necropolis in Feldioara (Transylvania) Gînguță, Alexandra Rusu, Ioana Mircea, Cristina Ioniță, Adrian Banciu, Horia L. Kelemen, Beatrice Genes (Basel) Article The genetic signature of modern Europeans is the cumulated result of millennia of discrete small-scale exchanges between multiple distinct population groups that performed a repeated cycle of movement, settlement, and interactions with each other. In this study we aimed to highlight one such minute genetic cycle in a sea of genetic interactions by reconstructing part of the genetic story of the migration, settlement, interaction, and legacy of what is today the Transylvanian Saxon. The analysis of the mitochondrial DNA control region of 13 medieval individuals from Feldioara necropolis (Transylvania region, Romania) reveals a genetically heterogeneous group where all identified haplotypes are different. Most of the perceived maternal lineages are of Western Eurasian origin, except for the Central Asiatic haplogroup C seen in only one sample. Comparisons with historical and modern populations describe the contribution of the investigated Saxon settlers to the genetic history of this part of Europe. MDPI 2021-03-19 /pmc/articles/PMC8003334/ /pubmed/33808521 http://dx.doi.org/10.3390/genes12030436 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ).
spellingShingle Article
Gînguță, Alexandra
Rusu, Ioana
Mircea, Cristina
Ioniță, Adrian
Banciu, Horia L.
Kelemen, Beatrice
Mitochondrial DNA Profiles of Individuals from a 12th Century Necropolis in Feldioara (Transylvania)
title Mitochondrial DNA Profiles of Individuals from a 12th Century Necropolis in Feldioara (Transylvania)
title_full Mitochondrial DNA Profiles of Individuals from a 12th Century Necropolis in Feldioara (Transylvania)
title_fullStr Mitochondrial DNA Profiles of Individuals from a 12th Century Necropolis in Feldioara (Transylvania)
title_full_unstemmed Mitochondrial DNA Profiles of Individuals from a 12th Century Necropolis in Feldioara (Transylvania)
title_short Mitochondrial DNA Profiles of Individuals from a 12th Century Necropolis in Feldioara (Transylvania)
title_sort mitochondrial dna profiles of individuals from a 12th century necropolis in feldioara (transylvania)
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003334/
https://www.ncbi.nlm.nih.gov/pubmed/33808521
http://dx.doi.org/10.3390/genes12030436
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