Petasis vs. Strecker Amino Acid Synthesis: Convergence, Divergence and Opportunities in Organic Synthesis

α-Amino acids find widespread applications in various areas of life and physical sciences. Their syntheses are carried out by a multitude of protocols, of which Petasis and Strecker reactions have emerged as the most straightforward and most widely used. Both reactions are three-component reactions...

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Detalles Bibliográficos
Autor principal: Masamba, Wayiza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003338/
https://www.ncbi.nlm.nih.gov/pubmed/33803879
http://dx.doi.org/10.3390/molecules26061707
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author Masamba, Wayiza
author_facet Masamba, Wayiza
author_sort Masamba, Wayiza
collection PubMed
description α-Amino acids find widespread applications in various areas of life and physical sciences. Their syntheses are carried out by a multitude of protocols, of which Petasis and Strecker reactions have emerged as the most straightforward and most widely used. Both reactions are three-component reactions using the same starting materials, except the nucleophilic species. The differences and similarities between these two important reactions are highlighted in this review.
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spelling pubmed-80033382021-03-28 Petasis vs. Strecker Amino Acid Synthesis: Convergence, Divergence and Opportunities in Organic Synthesis Masamba, Wayiza Molecules Review α-Amino acids find widespread applications in various areas of life and physical sciences. Their syntheses are carried out by a multitude of protocols, of which Petasis and Strecker reactions have emerged as the most straightforward and most widely used. Both reactions are three-component reactions using the same starting materials, except the nucleophilic species. The differences and similarities between these two important reactions are highlighted in this review. MDPI 2021-03-18 /pmc/articles/PMC8003338/ /pubmed/33803879 http://dx.doi.org/10.3390/molecules26061707 Text en © 2021 by the author. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Masamba, Wayiza
Petasis vs. Strecker Amino Acid Synthesis: Convergence, Divergence and Opportunities in Organic Synthesis
title Petasis vs. Strecker Amino Acid Synthesis: Convergence, Divergence and Opportunities in Organic Synthesis
title_full Petasis vs. Strecker Amino Acid Synthesis: Convergence, Divergence and Opportunities in Organic Synthesis
title_fullStr Petasis vs. Strecker Amino Acid Synthesis: Convergence, Divergence and Opportunities in Organic Synthesis
title_full_unstemmed Petasis vs. Strecker Amino Acid Synthesis: Convergence, Divergence and Opportunities in Organic Synthesis
title_short Petasis vs. Strecker Amino Acid Synthesis: Convergence, Divergence and Opportunities in Organic Synthesis
title_sort petasis vs. strecker amino acid synthesis: convergence, divergence and opportunities in organic synthesis
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003338/
https://www.ncbi.nlm.nih.gov/pubmed/33803879
http://dx.doi.org/10.3390/molecules26061707
work_keys_str_mv AT masambawayiza petasisvsstreckeraminoacidsynthesisconvergencedivergenceandopportunitiesinorganicsynthesis

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