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Longitudinal Event-Level Sexual Risk and Substance Use among Gay, Bisexual, and Other Men Who Have Sex with Men

(1) Background: Condomless anal sex and substance use are associated with STI risk among gay, bisexual, and other men who have sex with men (gbMSM). Our first study objective was to describe event-level sexual risk and substance use trends among gbMSM. Our second study objective was to describe subs...

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Autores principales: Sang, Jordan M., Cui, Zishan, Sereda, Paul, Armstrong, Heather L., Olarewaju, Gbolahan, Lal, Allan, Card, Kiffer G., Roth, Eric A., Hogg, Robert S., Moore, David M., Lachowsky, Nathan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003364/
https://www.ncbi.nlm.nih.gov/pubmed/33808675
http://dx.doi.org/10.3390/ijerph18063183
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author Sang, Jordan M.
Cui, Zishan
Sereda, Paul
Armstrong, Heather L.
Olarewaju, Gbolahan
Lal, Allan
Card, Kiffer G.
Roth, Eric A.
Hogg, Robert S.
Moore, David M.
Lachowsky, Nathan J.
author_facet Sang, Jordan M.
Cui, Zishan
Sereda, Paul
Armstrong, Heather L.
Olarewaju, Gbolahan
Lal, Allan
Card, Kiffer G.
Roth, Eric A.
Hogg, Robert S.
Moore, David M.
Lachowsky, Nathan J.
author_sort Sang, Jordan M.
collection PubMed
description (1) Background: Condomless anal sex and substance use are associated with STI risk among gay, bisexual, and other men who have sex with men (gbMSM). Our first study objective was to describe event-level sexual risk and substance use trends among gbMSM. Our second study objective was to describe substances associated with event-level sexual risk. (2) Methods: Data come from the Momentum Health Study in Vancouver, British Columbia and participants were recruited from 2012–2015, with follow-up until 2018. Stratified by self-reported HIV status, we used generalized estimating equations to assess trends of sexual event-level substance use and assessed interactions between substance use and time period on event-level higher risk sex defined as condomless anal sex with an HIV serodifferent or unknown status partner. (3) Results: Event-level higher risk anal sex increased across the study period among HIV-negative/unknown (baseline prevalence: 13% vs. study end prevalence: 29%) and HIV-positive gbMSM (baseline prevalence: 16% vs. study end prevalence: 38%). Among HIV-negative/unknown gbMSM, event-level erectile drug use increased, while alcohol use decreased over the study period. Overall, interactions between substance use and time on higher risk anal sex were not statistically significant, regardless of serostatus. However, we found a number of time-specific significant interactions for erectile drugs, poppers, Gamma-hydroxybutyrate (GHB), crystal methamphetamine and ecstasy/MDMA use among HIV-negative/unknown gbMSM. (4) Conclusion: Significant differences in substance use trends and associated risks exist and are varied among gbMSM by serostatus. These findings provide a more comprehensive understanding of the effects of event-level substance use on sexual risk through longitudinal follow-up of nearly six years.
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spelling pubmed-80033642021-03-28 Longitudinal Event-Level Sexual Risk and Substance Use among Gay, Bisexual, and Other Men Who Have Sex with Men Sang, Jordan M. Cui, Zishan Sereda, Paul Armstrong, Heather L. Olarewaju, Gbolahan Lal, Allan Card, Kiffer G. Roth, Eric A. Hogg, Robert S. Moore, David M. Lachowsky, Nathan J. Int J Environ Res Public Health Article (1) Background: Condomless anal sex and substance use are associated with STI risk among gay, bisexual, and other men who have sex with men (gbMSM). Our first study objective was to describe event-level sexual risk and substance use trends among gbMSM. Our second study objective was to describe substances associated with event-level sexual risk. (2) Methods: Data come from the Momentum Health Study in Vancouver, British Columbia and participants were recruited from 2012–2015, with follow-up until 2018. Stratified by self-reported HIV status, we used generalized estimating equations to assess trends of sexual event-level substance use and assessed interactions between substance use and time period on event-level higher risk sex defined as condomless anal sex with an HIV serodifferent or unknown status partner. (3) Results: Event-level higher risk anal sex increased across the study period among HIV-negative/unknown (baseline prevalence: 13% vs. study end prevalence: 29%) and HIV-positive gbMSM (baseline prevalence: 16% vs. study end prevalence: 38%). Among HIV-negative/unknown gbMSM, event-level erectile drug use increased, while alcohol use decreased over the study period. Overall, interactions between substance use and time on higher risk anal sex were not statistically significant, regardless of serostatus. However, we found a number of time-specific significant interactions for erectile drugs, poppers, Gamma-hydroxybutyrate (GHB), crystal methamphetamine and ecstasy/MDMA use among HIV-negative/unknown gbMSM. (4) Conclusion: Significant differences in substance use trends and associated risks exist and are varied among gbMSM by serostatus. These findings provide a more comprehensive understanding of the effects of event-level substance use on sexual risk through longitudinal follow-up of nearly six years. MDPI 2021-03-19 /pmc/articles/PMC8003364/ /pubmed/33808675 http://dx.doi.org/10.3390/ijerph18063183 Text en © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Sang, Jordan M.
Cui, Zishan
Sereda, Paul
Armstrong, Heather L.
Olarewaju, Gbolahan
Lal, Allan
Card, Kiffer G.
Roth, Eric A.
Hogg, Robert S.
Moore, David M.
Lachowsky, Nathan J.
Longitudinal Event-Level Sexual Risk and Substance Use among Gay, Bisexual, and Other Men Who Have Sex with Men
title Longitudinal Event-Level Sexual Risk and Substance Use among Gay, Bisexual, and Other Men Who Have Sex with Men
title_full Longitudinal Event-Level Sexual Risk and Substance Use among Gay, Bisexual, and Other Men Who Have Sex with Men
title_fullStr Longitudinal Event-Level Sexual Risk and Substance Use among Gay, Bisexual, and Other Men Who Have Sex with Men
title_full_unstemmed Longitudinal Event-Level Sexual Risk and Substance Use among Gay, Bisexual, and Other Men Who Have Sex with Men
title_short Longitudinal Event-Level Sexual Risk and Substance Use among Gay, Bisexual, and Other Men Who Have Sex with Men
title_sort longitudinal event-level sexual risk and substance use among gay, bisexual, and other men who have sex with men
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003364/
https://www.ncbi.nlm.nih.gov/pubmed/33808675
http://dx.doi.org/10.3390/ijerph18063183
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