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Seroprevalence of Anti-SARS-CoV-2 Antibodies in a Random Sample of Inhabitants of the Katowice Region, Poland

Lack of knowledge around seroprevalence levels of COVID-19 in Poland was the reason for the implementation of a seroepidemiological study in the Katowice Region (2,100,000 inhabitants). In October–November 2020, a questionnaire examination and measurement of anti-SARS-CoV-2 IgG and IgM antibodies we...

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Autores principales: Zejda, Jan E., Brożek, Grzegorz M., Kowalska, Małgorzata, Barański, Kamil, Kaleta-Pilarska, Angelina, Nowakowski, Artur, Xia, Yuchen, Buszman, Paweł
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003539/
https://www.ncbi.nlm.nih.gov/pubmed/33808716
http://dx.doi.org/10.3390/ijerph18063188
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author Zejda, Jan E.
Brożek, Grzegorz M.
Kowalska, Małgorzata
Barański, Kamil
Kaleta-Pilarska, Angelina
Nowakowski, Artur
Xia, Yuchen
Buszman, Paweł
author_facet Zejda, Jan E.
Brożek, Grzegorz M.
Kowalska, Małgorzata
Barański, Kamil
Kaleta-Pilarska, Angelina
Nowakowski, Artur
Xia, Yuchen
Buszman, Paweł
author_sort Zejda, Jan E.
collection PubMed
description Lack of knowledge around seroprevalence levels of COVID-19 in Poland was the reason for the implementation of a seroepidemiological study in the Katowice Region (2,100,000 inhabitants). In October–November 2020, a questionnaire examination and measurement of anti-SARS-CoV-2 IgG and IgM antibodies were performed in a random sample of the general population (n = 1167). The objectives of the study were to estimate the prevalence of IgG and IgM antibodies and to assess their host-related correlates. The prevalence of IgG seropositivity was 11.4% (95% CI: 9.5–13.2%) and IgM seropositivity was 4.6% (95% CI: 3.5–5.8%). Diagnosis of COVID-19 was found in 4.8% of subjects. A positive IgG test was statistically significantly associated with age (inverse relationship), a person’s contact with a COVID-19 patient, quarantine, and two symptoms in the past: fever and loss of smell/taste. Positive IgG tests were less prevalent in subjects who had diagnoses of arterial hypertension, diabetes, or rheumatologic disorders. IgM test positivity was associated with quarantine and loss of smell/taste only with no effect of chronic diseases found. In Poland, in the period October–November 2020, the prevalence of SARS-CoV-2 infection was larger than earlier estimates obtained in other European countries, probably reflecting the measurements obtained during the “second wave” of the epidemic.
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spelling pubmed-80035392021-03-28 Seroprevalence of Anti-SARS-CoV-2 Antibodies in a Random Sample of Inhabitants of the Katowice Region, Poland Zejda, Jan E. Brożek, Grzegorz M. Kowalska, Małgorzata Barański, Kamil Kaleta-Pilarska, Angelina Nowakowski, Artur Xia, Yuchen Buszman, Paweł Int J Environ Res Public Health Article Lack of knowledge around seroprevalence levels of COVID-19 in Poland was the reason for the implementation of a seroepidemiological study in the Katowice Region (2,100,000 inhabitants). In October–November 2020, a questionnaire examination and measurement of anti-SARS-CoV-2 IgG and IgM antibodies were performed in a random sample of the general population (n = 1167). The objectives of the study were to estimate the prevalence of IgG and IgM antibodies and to assess their host-related correlates. The prevalence of IgG seropositivity was 11.4% (95% CI: 9.5–13.2%) and IgM seropositivity was 4.6% (95% CI: 3.5–5.8%). Diagnosis of COVID-19 was found in 4.8% of subjects. A positive IgG test was statistically significantly associated with age (inverse relationship), a person’s contact with a COVID-19 patient, quarantine, and two symptoms in the past: fever and loss of smell/taste. Positive IgG tests were less prevalent in subjects who had diagnoses of arterial hypertension, diabetes, or rheumatologic disorders. IgM test positivity was associated with quarantine and loss of smell/taste only with no effect of chronic diseases found. In Poland, in the period October–November 2020, the prevalence of SARS-CoV-2 infection was larger than earlier estimates obtained in other European countries, probably reflecting the measurements obtained during the “second wave” of the epidemic. MDPI 2021-03-19 /pmc/articles/PMC8003539/ /pubmed/33808716 http://dx.doi.org/10.3390/ijerph18063188 Text en © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Zejda, Jan E.
Brożek, Grzegorz M.
Kowalska, Małgorzata
Barański, Kamil
Kaleta-Pilarska, Angelina
Nowakowski, Artur
Xia, Yuchen
Buszman, Paweł
Seroprevalence of Anti-SARS-CoV-2 Antibodies in a Random Sample of Inhabitants of the Katowice Region, Poland
title Seroprevalence of Anti-SARS-CoV-2 Antibodies in a Random Sample of Inhabitants of the Katowice Region, Poland
title_full Seroprevalence of Anti-SARS-CoV-2 Antibodies in a Random Sample of Inhabitants of the Katowice Region, Poland
title_fullStr Seroprevalence of Anti-SARS-CoV-2 Antibodies in a Random Sample of Inhabitants of the Katowice Region, Poland
title_full_unstemmed Seroprevalence of Anti-SARS-CoV-2 Antibodies in a Random Sample of Inhabitants of the Katowice Region, Poland
title_short Seroprevalence of Anti-SARS-CoV-2 Antibodies in a Random Sample of Inhabitants of the Katowice Region, Poland
title_sort seroprevalence of anti-sars-cov-2 antibodies in a random sample of inhabitants of the katowice region, poland
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003539/
https://www.ncbi.nlm.nih.gov/pubmed/33808716
http://dx.doi.org/10.3390/ijerph18063188
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