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Myxoma Virus Expressing LIGHT (TNFSF14) Pre-Loaded into Adipose-Derived Mesenchymal Stem Cells Is Effective Treatment for Murine Pancreatic Adenocarcinoma

SIMPLE SUMMARY: Pancreatic cancer is a deadly disease with no effective therapy. Oncolytic viruses such as myxoma (MYXV) have revealed great potential to treat malignancies, due to dual anti-cancer effects—oncolytic and immune-stimulating effects. We aimed to verify whether adipose-derived mesenchym...

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Detalles Bibliográficos
Autores principales: Jazowiecka-Rakus, Joanna, Hadrys, Agata, Rahman, Masmudur M., McFadden, Grant, Fidyk, Wojciech, Chmielik, Ewa, Pazdzior, Marlena, Grajek, Maciej, Kozik, Violetta, Sochanik, Aleksander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003548/
https://www.ncbi.nlm.nih.gov/pubmed/33808692
http://dx.doi.org/10.3390/cancers13061394