Melanin Distribution in Human Skin: Influence of Cytoskeletal, Polarity, and Centrosome-Related Machinery of Stratum basale Keratinocytes

Melanin granules cluster within supra-nuclear caps in basal keratinocytes (KCs) of the human epidermis, where they protect KC genomic DNA against ultraviolet radiation (UVR) damage. While much is known about melanogenesis in melanocytes (MCs) and a moderate amount about melanin transfer from MC to K...

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Detalles Bibliográficos
Autores principales: Castellano-Pellicena, Irene, Morrison, Ciaran G., Bell, Mike, O’Connor, Clare, Tobin, Desmond J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003549/
https://www.ncbi.nlm.nih.gov/pubmed/33808676
http://dx.doi.org/10.3390/ijms22063143

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003549/
https://www.ncbi.nlm.nih.gov/pubmed/33808676
http://dx.doi.org/10.3390/ijms22063143

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