Cargando…

Melanin Distribution in Human Skin: Influence of Cytoskeletal, Polarity, and Centrosome-Related Machinery of Stratum basale Keratinocytes

Melanin granules cluster within supra-nuclear caps in basal keratinocytes (KCs) of the human epidermis, where they protect KC genomic DNA against ultraviolet radiation (UVR) damage. While much is known about melanogenesis in melanocytes (MCs) and a moderate amount about melanin transfer from MC to K...

Descripción completa

Detalles Bibliográficos
Autores principales:	Castellano-Pellicena, Irene, Morrison, Ciaran G., Bell, Mike, O’Connor, Clare, Tobin, Desmond J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003549/ https://www.ncbi.nlm.nih.gov/pubmed/33808676 http://dx.doi.org/10.3390/ijms22063143

Ejemplares similares

Dynamic Association of Proteasomal Machinery with the Centrosome
por: Christian Wigley, W., et al.
Publicado: (1999)

Melanin’s Journey from Melanocytes to Keratinocytes: Uncovering the Molecular Mechanisms of Melanin Transfer and Processing
por: Bento-Lopes, Liliana, et al.
Publicado: (2023)

Keratinocyte cytoskeletal roles in cell sheet engineering
por: Wei, Qi, et al.
Publicado: (2013)

Nek5 promotes centrosome integrity in interphase and loss of centrosome cohesion in mitosis
por: Prosser, Suzanna L., et al.
Publicado: (2015)

A Centrosome-autonomous Signal That Involves Centriole Disengagement Permits Centrosome Duplication in G2 Phase after DNA Damage
por: Inanç, Burcu, et al.
Publicado: (2010)

Centrosome-free basal MT organization
por: LeBrasseur, Nicole
Publicado: (2005)

Melanin distribution from the dermal–epidermal junction to the stratum corneum: non-invasive in vivo assessment by fluorescence and Raman microspectroscopy
por: Yakimov, B. P., et al.
Publicado: (2020)

Elucidating the molecular landscape of the stratum corneum
por: Starr, Nichola J., et al.
Publicado: (2022)

Catalase Activity in Keratinocytes, Stratum Corneum, and Defatted Algae Biomass as a Potential Skin Care Ingredient
por: Szczepanczyk, Michal, et al.
Publicado: (2021)

The Centrioles, Centrosomes, Basal Bodies, and Cilia of Drosophila melanogaster
por: Lattao, Ramona, et al.
Publicado: (2017)

Centriole splitting caused by loss of the centrosomal linker protein C-NAP1 reduces centriolar satellite density and impedes centrosome amplification
por: Flanagan, Anne-Marie, et al.
Publicado: (2017)

Opsin 3 mediates UVA-induced keratinocyte supranuclear melanin cap formation
por: Lan, Yinghua, et al.
Publicado: (2023)

Identification and localization of a novel, cytoskeletal, centrosome- associated protein in PtK2 cells
Publicado: (1988)

Visualising the cytoskeletal machinery in neuronal growth cones using cryo-electron tomography
por: Atherton, Joseph, et al.
Publicado: (2022)

Loss of ‘Epidermal Melanin Unit’ Integrity in Human Skin During Melanoma-Genesis
por: Casalou, Cristina, et al.
Publicado: (2022)

Is There a Relationship between the Stratum Corneum Thickness and That of the Viable Parts of Tumour Cells in Basal Cell Carcinoma?
por: Foss, Olav A., et al.
Publicado: (2016)

The centrosomal OFD1 protein interacts with the translation machinery and regulates the synthesis of specific targets
por: Iaconis, Daniela, et al.
Publicado: (2017)

Centrosomal Localization of the Psoriasis Candidate Gene Product, CCHCR1, Supports a Role in Cytoskeletal Organization
por: Tervaniemi, Mari H., et al.
Publicado: (2012)

RAB3A Regulates Melanin Exocytosis and Transfer Induced by Keratinocyte-Conditioned Medium
por: Cabaço, Luís C., et al.
Publicado: (2022)

Stratum corneum dysfunction in dandruff
por: Turner, G A, et al.
Publicado: (2012)

Abnormal centrosomal structure and duplication in Cep135-deficient vertebrate cells
por: Inanç, Burcu, et al.
Publicado: (2013)

Maintenance of the corneal epithelium is carried out by germinative cells of its basal stratum and not by presumed stem cells of the limbus
por: Haddad, A., et al.
Publicado: (2014)

Beyond the Epidermal-Melanin-Unit: The Human Scalp Anagen Hair Bulb Is Home to Multiple Melanocyte Subpopulations of Variable Melanogenic Capacity
por: Casalou, Cristina, et al.
Publicado: (2023)

The signaling involved in autophagy machinery in keratinocytes and therapeutic approaches for skin diseases
por: Li, Li, et al.
Publicado: (2016)

Structural centrosome aberrations sensitize polarized epithelia to basal cell extrusion
por: Ganier, Olivier, et al.
Publicado: (2018)

Defective nucleotide excision repair with normal centrosome structures and functions in the absence of all vertebrate centrins
por: Dantas, Tiago J., et al.
Publicado: (2011)

The basal transcription machinery as a target for cancer therapy
por: Villicaña, Claudia, et al.
Publicado: (2014)

Hyaluronan-Phosphatidylethanolamine Polymers Form Pericellular Coats on Keratinocytes and Promote Basal Keratinocyte Proliferation
por: Symonette, Caitlin J., et al.
Publicado: (2014)

Drosophila pericentrin requires interaction with calmodulin for its function at centrosomes and neuronal basal bodies but not at sperm basal bodies
por: Galletta, Brian J., et al.
Publicado: (2014)

Intracellular signalling pathways and cytoskeletal functions converge on the psoriasis candidate gene CCHCR1 expressed at P-bodies and centrosomes
por: Tervaniemi, Mari H., et al.
Publicado: (2018)

Centrosomes in the zebrafish (Danio rerio): a review including the related basal body
por: Lessman, Charles A
Publicado: (2012)

Menopause induces changes to the stratum corneum ceramide profile, which are prevented by hormone replacement therapy
por: Kendall, Alexandra C., et al.
Publicado: (2022)

Aggresome assembly at the centrosome is driven by CP110–CEP97–CEP290 and centriolar satellites
por: Prosser, Suzanna L., et al.
Publicado: (2022)

Profilin-1; a novel regulator of DNA damage response and repair machinery in keratinocytes
por: Lee, Chang-Jin, et al.
Publicado: (2021)

The Centrosomal Protein Pericentrin Identified at the Basal Body Complex of the Connecting Cilium in Mouse Photoreceptors
por: Mühlhans, Johanna, et al.
Publicado: (2011)

The human sperm basal body is a complex centrosome important for embryo preimplantation development
por: Amargant, Farners, et al.
Publicado: (2021)

Amyloid β Induces Early Changes in the Ribosomal Machinery, Cytoskeletal Organization and Oxidative Phosphorylation in Retinal Photoreceptor Cells
por: Deng, Liting, et al.
Publicado: (2019)

Prostaglandin D(2) production in FM55 melanoma cells is regulated by α-melanocyte-stimulating hormone and is not related to melanin production
por: Masoodi, Mojgan, et al.
Publicado: (2010)

The basal ganglia, the ideal machinery for the cost-benefit analysis of action plans
por: Hwang, Eun Jung
Publicado: (2013)

Mediator is an intrinsic component of the basal RNA polymerase II machinery in vivo
por: Lacombe, Thierry, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_i03ugmbph6irbedleifm2kgi3t