Iron-Bound Lipocalin-2 from Tumor-Associated Macrophages Drives Breast Cancer Progression Independent of Ferroportin

Macrophages supply iron to the breast tumor microenvironment by enforced secretion of lipocalin-2 (Lcn-2)-bound iron as well as the increased expression of the iron exporter ferroportin (FPN). We aimed at identifying the contribution of each pathway in supplying iron for the growing tumor, thereby f...

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Detalles Bibliográficos
Autores principales: Mertens, Christina, Schnetz, Matthias, Rehwald, Claudia, Grein, Stephan, Elwakeel, Eiman, Weigert, Andreas, Brüne, Bernhard, Jung, Michaela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003561/
https://www.ncbi.nlm.nih.gov/pubmed/33808732
http://dx.doi.org/10.3390/metabo11030180

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003561/
https://www.ncbi.nlm.nih.gov/pubmed/33808732
http://dx.doi.org/10.3390/metabo11030180

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