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Site-Selective Artificial Ribonucleases: Renaissance of Oligonucleotide Conjugates for Irreversible Cleavage of RNA Sequences

RNA-targeting therapeutics require highly efficient sequence-specific devices capable of RNA irreversible degradation in vivo. The most developed methods of sequence-specific RNA cleavage, such as siRNA or antisense oligonucleotides (ASO), are currently based on recruitment of either intracellular m...

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Detalles Bibliográficos
Autores principales:	Staroseletz, Yaroslav, Gaponova, Svetlana, Patutina, Olga, Bichenkova, Elena, Amirloo, Bahareh, Heyman, Thomas, Chiglintseva, Daria, Zenkova, Marina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003597/ https://www.ncbi.nlm.nih.gov/pubmed/33808835 http://dx.doi.org/10.3390/molecules26061732

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