Synthesis and Biological Evaluation of 2,3,4-Triaryl-1,2,4-oxadiazol-5-ones as p38 MAPK Inhibitors

A series of azastilbene derivatives, characterized by the presence of the 1,2,4-oxadiazole-5-one system as a linker of the two aromatic rings of stilbenes, have been prepared as novel potential inhibitors of p38 MAPK. Biological assays indicated that some of the synthesized compounds are endowed wit...

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Detalles Bibliográficos
Autores principales: Romeo, Roberto, Giofrè, Salvatore V., Chiacchio, Maria A., Veltri, Lucia, Celesti, Consuelo, Iannazzo, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003627/
https://www.ncbi.nlm.nih.gov/pubmed/33804659
http://dx.doi.org/10.3390/molecules26061745

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003627/
https://www.ncbi.nlm.nih.gov/pubmed/33804659
http://dx.doi.org/10.3390/molecules26061745

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