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A Household-Based Survey of Iodine Nutrition in Moroccan Children Shows Iodine Sufficiency at the National Level But Risk of Deficient Intakes in Mountainous Areas

Historically, mountainous areas of Morocco have been affected by endemic goiter and severe iodine deficiency. In 1995, Morocco legislated salt iodization to reduce iodine deficiency. There has been no national survey of iodine nutrition in school-age children for nearly 3 decades. Our aim was to ass...

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Autores principales: El Ammari, Laila, Saeid, Naima, Talouizte, Anouar, Gamih, Hasnae, Labzizi, Salwa, Mendili, Jamila El, Rami, Anass, Idrissi, Mohamed, Benjeddou, Kaoutar, Zahrou, Fatima ezzahra, Elmzibri, Mohamed, Brown, Amal Tucker, Al-Jawaldeh, Ayoub, Yahyane, Abdelhakim, Zimmerman, Michael Bruce, Kari, Khalid El, Aguenaou, Hassan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003689/
https://www.ncbi.nlm.nih.gov/pubmed/33808824
http://dx.doi.org/10.3390/children8030240
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author El Ammari, Laila
Saeid, Naima
Talouizte, Anouar
Gamih, Hasnae
Labzizi, Salwa
Mendili, Jamila El
Rami, Anass
Idrissi, Mohamed
Benjeddou, Kaoutar
Zahrou, Fatima ezzahra
Elmzibri, Mohamed
Brown, Amal Tucker
Al-Jawaldeh, Ayoub
Yahyane, Abdelhakim
Zimmerman, Michael Bruce
Kari, Khalid El
Aguenaou, Hassan
author_facet El Ammari, Laila
Saeid, Naima
Talouizte, Anouar
Gamih, Hasnae
Labzizi, Salwa
Mendili, Jamila El
Rami, Anass
Idrissi, Mohamed
Benjeddou, Kaoutar
Zahrou, Fatima ezzahra
Elmzibri, Mohamed
Brown, Amal Tucker
Al-Jawaldeh, Ayoub
Yahyane, Abdelhakim
Zimmerman, Michael Bruce
Kari, Khalid El
Aguenaou, Hassan
author_sort El Ammari, Laila
collection PubMed
description Historically, mountainous areas of Morocco have been affected by endemic goiter and severe iodine deficiency. In 1995, Morocco legislated salt iodization to reduce iodine deficiency. There has been no national survey of iodine nutrition in school-age children for nearly 3 decades. Our aim was to assess iodine nutrition in a national sample of 6–12-year-old children in Morocco to inform the national salt iodization strategy. In this cross-sectional household-based survey, we randomly recruited healthy 6–12-year-old children from 180 clusters in four geographic zones (north and east, central, north and south) covering the 12 regions of Morocco. A questionnaire was completed, including socio-economic status and parental level of education. In addition, anthropometric measurements were taken to assess nutrition status, and a spot urine sample was collected to measure urinary iodine concentration (UIC). A total of 3118 households were surveyed, and 1043 eligible children were recruited, 56% from urban areas and 44% from rural areas. At the national level, the percentage of surveyed samples with UIC < 50 μg/L was 21.6% (19.2%; 24.2%), which exceeds the WHO suggestion of no more than 20% of samples below 50 μg/L, despite an adequate level of median urinary iodine concentration (mUIC) at 117.4 µg/L (110.2; 123.3). There were no statistically significant differences in mUIC comparing urban vs. rural areas and socio-economic status. However, the mUIC was significantly lower in the central (high-altitude non-coastal) zone (p < 0.004), where the mUIC (95% CI) was deficient at 89.2 µg/L (80.8; 102.9). There was also a significant difference in the mUIC by head of household education level (p = 0.008). The mUIC in Moroccan children >100 µg/L indicates iodine sufficiency at the national level. However, the percentage of surveyed samples with UIC < 50 μg/L above suggests that a significant proportion of children remain at risk for iodine deficiency, and it appears those at greatest risk are residing in the central (high altitude non-coastal) zone. A national level mUIC value may conceal discrepancies in iodine intake among different sub-groups, including those defined by geographic region.
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spelling pubmed-80036892021-03-28 A Household-Based Survey of Iodine Nutrition in Moroccan Children Shows Iodine Sufficiency at the National Level But Risk of Deficient Intakes in Mountainous Areas El Ammari, Laila Saeid, Naima Talouizte, Anouar Gamih, Hasnae Labzizi, Salwa Mendili, Jamila El Rami, Anass Idrissi, Mohamed Benjeddou, Kaoutar Zahrou, Fatima ezzahra Elmzibri, Mohamed Brown, Amal Tucker Al-Jawaldeh, Ayoub Yahyane, Abdelhakim Zimmerman, Michael Bruce Kari, Khalid El Aguenaou, Hassan Children (Basel) Article Historically, mountainous areas of Morocco have been affected by endemic goiter and severe iodine deficiency. In 1995, Morocco legislated salt iodization to reduce iodine deficiency. There has been no national survey of iodine nutrition in school-age children for nearly 3 decades. Our aim was to assess iodine nutrition in a national sample of 6–12-year-old children in Morocco to inform the national salt iodization strategy. In this cross-sectional household-based survey, we randomly recruited healthy 6–12-year-old children from 180 clusters in four geographic zones (north and east, central, north and south) covering the 12 regions of Morocco. A questionnaire was completed, including socio-economic status and parental level of education. In addition, anthropometric measurements were taken to assess nutrition status, and a spot urine sample was collected to measure urinary iodine concentration (UIC). A total of 3118 households were surveyed, and 1043 eligible children were recruited, 56% from urban areas and 44% from rural areas. At the national level, the percentage of surveyed samples with UIC < 50 μg/L was 21.6% (19.2%; 24.2%), which exceeds the WHO suggestion of no more than 20% of samples below 50 μg/L, despite an adequate level of median urinary iodine concentration (mUIC) at 117.4 µg/L (110.2; 123.3). There were no statistically significant differences in mUIC comparing urban vs. rural areas and socio-economic status. However, the mUIC was significantly lower in the central (high-altitude non-coastal) zone (p < 0.004), where the mUIC (95% CI) was deficient at 89.2 µg/L (80.8; 102.9). There was also a significant difference in the mUIC by head of household education level (p = 0.008). The mUIC in Moroccan children >100 µg/L indicates iodine sufficiency at the national level. However, the percentage of surveyed samples with UIC < 50 μg/L above suggests that a significant proportion of children remain at risk for iodine deficiency, and it appears those at greatest risk are residing in the central (high altitude non-coastal) zone. A national level mUIC value may conceal discrepancies in iodine intake among different sub-groups, including those defined by geographic region. MDPI 2021-03-19 /pmc/articles/PMC8003689/ /pubmed/33808824 http://dx.doi.org/10.3390/children8030240 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ).
spellingShingle Article
El Ammari, Laila
Saeid, Naima
Talouizte, Anouar
Gamih, Hasnae
Labzizi, Salwa
Mendili, Jamila El
Rami, Anass
Idrissi, Mohamed
Benjeddou, Kaoutar
Zahrou, Fatima ezzahra
Elmzibri, Mohamed
Brown, Amal Tucker
Al-Jawaldeh, Ayoub
Yahyane, Abdelhakim
Zimmerman, Michael Bruce
Kari, Khalid El
Aguenaou, Hassan
A Household-Based Survey of Iodine Nutrition in Moroccan Children Shows Iodine Sufficiency at the National Level But Risk of Deficient Intakes in Mountainous Areas
title A Household-Based Survey of Iodine Nutrition in Moroccan Children Shows Iodine Sufficiency at the National Level But Risk of Deficient Intakes in Mountainous Areas
title_full A Household-Based Survey of Iodine Nutrition in Moroccan Children Shows Iodine Sufficiency at the National Level But Risk of Deficient Intakes in Mountainous Areas
title_fullStr A Household-Based Survey of Iodine Nutrition in Moroccan Children Shows Iodine Sufficiency at the National Level But Risk of Deficient Intakes in Mountainous Areas
title_full_unstemmed A Household-Based Survey of Iodine Nutrition in Moroccan Children Shows Iodine Sufficiency at the National Level But Risk of Deficient Intakes in Mountainous Areas
title_short A Household-Based Survey of Iodine Nutrition in Moroccan Children Shows Iodine Sufficiency at the National Level But Risk of Deficient Intakes in Mountainous Areas
title_sort household-based survey of iodine nutrition in moroccan children shows iodine sufficiency at the national level but risk of deficient intakes in mountainous areas
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003689/
https://www.ncbi.nlm.nih.gov/pubmed/33808824
http://dx.doi.org/10.3390/children8030240
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