Cargando…
PAI-1 in Diabetes: Pathophysiology and Role as a Therapeutic Target
Hypofibrinolysis is a key abnormality in diabetes and contributes to the adverse vascular outcome in this population. Plasminogen activator inhibitor (PAI)-1 is an important regulator of the fibrinolytic process and levels of this antifibrinolytic protein are elevated in diabetes and insulin resista...
Autores principales: | Altalhi, Rawan, Pechlivani, Nikoletta, Ajjan, Ramzi A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003717/ https://www.ncbi.nlm.nih.gov/pubmed/33804680 http://dx.doi.org/10.3390/ijms22063170 |
Ejemplares similares
-
Thrombosis and Vascular Inflammation in Diabetes: Mechanisms and Potential Therapeutic Targets
por: Pechlivani, Nikoletta, et al.
Publicado: (2018) -
Fibrinogen and Antifibrinolytic Proteins: Interactions and Future Therapeutics
por: Pechlivani, Nikoletta, et al.
Publicado: (2021) -
Plasmin Inhibitor in Health and Diabetes: Role of the Protein as a Therapeutic Target
por: Alsayejh, Basmah, et al.
Publicado: (2022) -
Non-Traditional Pathways for Platelet Pathophysiology in Diabetes: Implications for Future Therapeutic Targets
por: Sagar, Rebecca C., et al.
Publicado: (2022) -
Hypofibrinolysis in diabetes: a therapeutic target for the reduction of cardiovascular risk
por: Kearney, Katherine, et al.
Publicado: (2017)