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Marine-Derived Natural Products as ATP-Competitive mTOR Kinase Inhibitors for Cancer Therapeutics

The mammalian target of rapamycin (mTOR) is a serine/threonine kinase portraying a quintessential role in cellular proliferation and survival. Aberrations in the mTOR signaling pathway have been reported in numerous cancers including thyroid, lung, gastric and ovarian cancer, thus making it a therap...

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Detalles Bibliográficos
Autores principales:	Parate, Shraddha, Kumar, Vikas, Lee, Gihwan, Rampogu, Shailima, Hong, Jong Chan, Lee, Keun Woo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003863/ https://www.ncbi.nlm.nih.gov/pubmed/33801030 http://dx.doi.org/10.3390/ph14030282

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