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The Prognostic and Predictive Role of Somatic BRCA Mutations in Ovarian Cancer: Results from a Multicenter Cohort Study

Previous research involving epithelial ovarian cancer patients showed that, compared to germline BRCA (gBRCA) mutations, somatic BRCA (sBRCA) mutations present a similar positive impact with regard to overall survival (OS) and platinum and PARP (poly (ADP-ribose) polymerase) inhibitor sensitivity. N...

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Detalles Bibliográficos
Autores principales: Toss, Angela, Piombino, Claudia, Tenedini, Elena, Bologna, Alessandra, Gasparini, Elisa, Tarantino, Vittoria, Filieri, Maria Elisabetta, Cottafavi, Luca, Giovanardi, Filippo, Madrigali, Stefano, Civallero, Monica, Marcheselli, Luigi, Marchi, Isabella, Domati, Federica, Venturelli, Marta, Barbieri, Elena, Grandi, Giovanni, Tagliafico, Enrico, Cortesi, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003908/
https://www.ncbi.nlm.nih.gov/pubmed/33801055
http://dx.doi.org/10.3390/diagnostics11030565