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The Prognostic and Predictive Role of Somatic BRCA Mutations in Ovarian Cancer: Results from a Multicenter Cohort Study
Previous research involving epithelial ovarian cancer patients showed that, compared to germline BRCA (gBRCA) mutations, somatic BRCA (sBRCA) mutations present a similar positive impact with regard to overall survival (OS) and platinum and PARP (poly (ADP-ribose) polymerase) inhibitor sensitivity. N...
Autores principales: | Toss, Angela, Piombino, Claudia, Tenedini, Elena, Bologna, Alessandra, Gasparini, Elisa, Tarantino, Vittoria, Filieri, Maria Elisabetta, Cottafavi, Luca, Giovanardi, Filippo, Madrigali, Stefano, Civallero, Monica, Marcheselli, Luigi, Marchi, Isabella, Domati, Federica, Venturelli, Marta, Barbieri, Elena, Grandi, Giovanni, Tagliafico, Enrico, Cortesi, Laura |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003908/ https://www.ncbi.nlm.nih.gov/pubmed/33801055 http://dx.doi.org/10.3390/diagnostics11030565 |
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