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Limosilactobacillus fermentum CECT5716: Mechanisms and Therapeutic Insights
Probiotics microorganisms exert their health-associated activities through some of the following general actions: competitive exclusion, enhancement of intestinal barrier function, production of bacteriocins, improvement of altered microbiota, and modulation of the immune response. Among them, Limos...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003974/ https://www.ncbi.nlm.nih.gov/pubmed/33801082 http://dx.doi.org/10.3390/nu13031016 |
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author | Rodríguez-Sojo, María Jesús Ruiz-Malagón, Antonio Jesús Rodríguez-Cabezas, María Elena Gálvez, Julio Rodríguez-Nogales, Alba |
author_facet | Rodríguez-Sojo, María Jesús Ruiz-Malagón, Antonio Jesús Rodríguez-Cabezas, María Elena Gálvez, Julio Rodríguez-Nogales, Alba |
author_sort | Rodríguez-Sojo, María Jesús |
collection | PubMed |
description | Probiotics microorganisms exert their health-associated activities through some of the following general actions: competitive exclusion, enhancement of intestinal barrier function, production of bacteriocins, improvement of altered microbiota, and modulation of the immune response. Among them, Limosilactobacillus fermentum CECT5716 has become one of the most promising probiotics and it has been described to possess potential beneficial effects on inflammatory processes and immunological alterations. Different studies, preclinical and clinical trials, have evidenced its anti-inflammatory and immunomodulatory properties and elucidated the precise mechanisms of action involved in its beneficial effects. Therefore, the aim of this review is to provide an updated overview of the effect on host health, mechanisms, and future therapeutic approaches. |
format | Online Article Text |
id | pubmed-8003974 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-80039742021-03-28 Limosilactobacillus fermentum CECT5716: Mechanisms and Therapeutic Insights Rodríguez-Sojo, María Jesús Ruiz-Malagón, Antonio Jesús Rodríguez-Cabezas, María Elena Gálvez, Julio Rodríguez-Nogales, Alba Nutrients Review Probiotics microorganisms exert their health-associated activities through some of the following general actions: competitive exclusion, enhancement of intestinal barrier function, production of bacteriocins, improvement of altered microbiota, and modulation of the immune response. Among them, Limosilactobacillus fermentum CECT5716 has become one of the most promising probiotics and it has been described to possess potential beneficial effects on inflammatory processes and immunological alterations. Different studies, preclinical and clinical trials, have evidenced its anti-inflammatory and immunomodulatory properties and elucidated the precise mechanisms of action involved in its beneficial effects. Therefore, the aim of this review is to provide an updated overview of the effect on host health, mechanisms, and future therapeutic approaches. MDPI 2021-03-21 /pmc/articles/PMC8003974/ /pubmed/33801082 http://dx.doi.org/10.3390/nu13031016 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ). |
spellingShingle | Review Rodríguez-Sojo, María Jesús Ruiz-Malagón, Antonio Jesús Rodríguez-Cabezas, María Elena Gálvez, Julio Rodríguez-Nogales, Alba Limosilactobacillus fermentum CECT5716: Mechanisms and Therapeutic Insights |
title | Limosilactobacillus fermentum CECT5716: Mechanisms and Therapeutic Insights |
title_full | Limosilactobacillus fermentum CECT5716: Mechanisms and Therapeutic Insights |
title_fullStr | Limosilactobacillus fermentum CECT5716: Mechanisms and Therapeutic Insights |
title_full_unstemmed | Limosilactobacillus fermentum CECT5716: Mechanisms and Therapeutic Insights |
title_short | Limosilactobacillus fermentum CECT5716: Mechanisms and Therapeutic Insights |
title_sort | limosilactobacillus fermentum cect5716: mechanisms and therapeutic insights |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003974/ https://www.ncbi.nlm.nih.gov/pubmed/33801082 http://dx.doi.org/10.3390/nu13031016 |
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