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Mast Cell Mediated Regulation of Small Intestinal Chloride Malabsorption in SAMP1/YitFc Mouse Model of Spontaneous Chronic Ileitis

In Inflammatory Bowel Disease (IBD), malabsorption of electrolytes (NaCl) results in diarrhea. Inhibition of coupled NaCl absorption, mediated by the dual operation of Na:H and Cl:HCO(3) exchangers on the brush border membrane (BBM) of the intestinal villus cells has been reported in IBD. In the SAM...

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Detalles Bibliográficos
Autores principales: Rahman, M Motiur, Afroz, Sheuli, Arthur, Subha, Sundaram, Uma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8004028/
https://www.ncbi.nlm.nih.gov/pubmed/33801010
http://dx.doi.org/10.3390/cells10030697