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Identifying Molecular Signatures of Distinct Modes of Collective Migration in Response to the Microenvironment Using Three-Dimensional Breast Cancer Models
SIMPLE SUMMARY: The objective of this study was to investigate the role of two microenvironmental factors, namely, tumor-intrinsic hypoxia and secretome in inducing collective migration. We utilized three-dimensional (3D) discrete-sized microtumor models, which recapitulate hallmarks of transition o...
Autores principales: | Ardila, Diana Catalina, Aggarwal, Vaishali, Singh, Manjulata, Chattopadhyay, Ansuman, Chaparala, Srilakshmi, Sant, Shilpa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8004051/ https://www.ncbi.nlm.nih.gov/pubmed/33804802 http://dx.doi.org/10.3390/cancers13061429 |
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