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In Silico Analysis of Huntingtin Homologs in Lower Eukaryotes
Huntington’s disease is a rare neurodegenerative and autosomal dominant disorder. HD is caused by a mutation in the gene coding for huntingtin (Htt). The result is the production of a mutant Htt with an abnormally long polyglutamine repeat that leads to pathological Htt aggregates. Although the stru...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8004120/ https://www.ncbi.nlm.nih.gov/pubmed/33809947 http://dx.doi.org/10.3390/ijms22063214 |