Brown Spiders’ Phospholipases-D with Potential Therapeutic Applications: Functional Assessment of Mutant Isoforms

Phospholipases-D (PLDs) found in Loxosceles spiders’ venoms are responsible for the dermonecrosis triggered by envenomation. PLDs can also induce other local and systemic effects, such as massive inflammatory response, edema, and hemolysis. Recombinant PLDs reproduce all of the deleterious effects i...

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Detalles Bibliográficos
Autores principales: da Silva, Thaís Pereira, de Castro, Fernando Jacomini, Vuitika, Larissa, Polli, Nayanne Louise Costacurta, Antunes, Bruno César, Bóia-Ferreira, Marianna, Minozzo, João Carlos, Mariutti, Ricardo Barros, Matsubara, Fernando Hitomi, Arni, Raghuvir Krishnaswamy, Wille, Ana Carolina Martins, Senff-Ribeiro, Andrea, Gremski, Luiza Helena, Veiga, Silvio Sanches
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8004160/
https://www.ncbi.nlm.nih.gov/pubmed/33801128
http://dx.doi.org/10.3390/biomedicines9030320

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