Increased Levels of ER Stress and Apoptosis in a Sheep Model for Pulmonary Fibrosis Are Alleviated by In Vivo Blockade of the KCa3.1 Ion Channel

Idiopathic pulmonary fibrosis (IPF) is a fatal interstitial lung disease, characterized by progressive damage to the lung tissues. Apoptosis and endoplasmic reticulum stress (ER stress) in type II alveolar epithelial cells (AECs) and lung macrophages have been linked with the development of IPF. The...

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Detalles Bibliográficos
Autores principales: Perera, Udari E., Organ, Louise, Dewage, Sasika N. V., Derseh, Habtamu B., Stent, Andrew, Snibson, Kenneth J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8004363/
https://www.ncbi.nlm.nih.gov/pubmed/33828632
http://dx.doi.org/10.1155/2021/6683195

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