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The evaluation of degeneration of posterior cruciate ligament using CT Hounsfield unit in knee osteoarthritis
BACKGROUND: Posterior cruciate ligament (PCL) degeneration is often seen in knee osteoarthritis (OA); however, there is no established method for its evaluation. The purpose of this study is to investigate whether the Hounsfield unit (HU) using computed tomography (CT) could be a useful scale to eva...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8004421/ https://www.ncbi.nlm.nih.gov/pubmed/33771140 http://dx.doi.org/10.1186/s12891-021-04177-w |
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author | Sumida, Yoshikazu Nakasa, Tomoyuki Ishikawa, Masakazu Nakamae, Atsuo Adachi, Nobuo |
author_facet | Sumida, Yoshikazu Nakasa, Tomoyuki Ishikawa, Masakazu Nakamae, Atsuo Adachi, Nobuo |
author_sort | Sumida, Yoshikazu |
collection | PubMed |
description | BACKGROUND: Posterior cruciate ligament (PCL) degeneration is often seen in knee osteoarthritis (OA); however, there is no established method for its evaluation. The purpose of this study is to investigate whether the Hounsfield unit (HU) using computed tomography (CT) could be a useful scale to evaluate the degeneration of PCL in knee OA. METHODS: Knee OA treated with total knee arthroplasty (21 patients, 21 knees) and non-osteoarthritic knees (21 patients, 21 knees) were retrospectively observed and studied. All PCLs in the knees were analyzed using CT. The PCL in the sagittal section was divided into three regions: proximal, middle, and distal sections. The HU value of the PCL at each area was measured. In osteoarthritic knees, tissues from the PCL were collected and histologically graded. The correlation between the radiological classification by Kellgren and Lawrence and the histological grade was analyzed. The average CT HU values for each degenerative grade were also calculated and compared. RESULTS: The HU values in OA and non-OA were 70.7 and 88.4 HU (p < 0.05) at the proximal region, 75.7 and 85.3 HU (p < 0.05) in the central region, and 82.3 and 86.5 HU (p > 0.05) in the distal region, respectively. The degeneration of PCL was graded as follows: one, three, and 17 mild, moderate, and severe cases at the proximal portion, and 16, 4, and one mild, moderate, and severe cases at the distal portion, respectively. The radiological classification and the grade of degeneration were not correlated in either the proximal (r = 0.047, p = 0.84) or the distal (r = − 0.21, p = 0.35) portions. The HU value was 84.5, 72.1, and 70.6 HU for mild, moderate, and severe grades, respectively (mild versus moderate: p < 0.05, mild versus severe: p < 0.05, moderate versus severe: p > 0.05). CONCLUSIONS: In knee OA, a lower HU value in the PCL indicates the progression of degeneration. The CT HU value could be a useful measurement to predict the grade of PCL degeneration. |
format | Online Article Text |
id | pubmed-8004421 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-80044212021-03-30 The evaluation of degeneration of posterior cruciate ligament using CT Hounsfield unit in knee osteoarthritis Sumida, Yoshikazu Nakasa, Tomoyuki Ishikawa, Masakazu Nakamae, Atsuo Adachi, Nobuo BMC Musculoskelet Disord Research Article BACKGROUND: Posterior cruciate ligament (PCL) degeneration is often seen in knee osteoarthritis (OA); however, there is no established method for its evaluation. The purpose of this study is to investigate whether the Hounsfield unit (HU) using computed tomography (CT) could be a useful scale to evaluate the degeneration of PCL in knee OA. METHODS: Knee OA treated with total knee arthroplasty (21 patients, 21 knees) and non-osteoarthritic knees (21 patients, 21 knees) were retrospectively observed and studied. All PCLs in the knees were analyzed using CT. The PCL in the sagittal section was divided into three regions: proximal, middle, and distal sections. The HU value of the PCL at each area was measured. In osteoarthritic knees, tissues from the PCL were collected and histologically graded. The correlation between the radiological classification by Kellgren and Lawrence and the histological grade was analyzed. The average CT HU values for each degenerative grade were also calculated and compared. RESULTS: The HU values in OA and non-OA were 70.7 and 88.4 HU (p < 0.05) at the proximal region, 75.7 and 85.3 HU (p < 0.05) in the central region, and 82.3 and 86.5 HU (p > 0.05) in the distal region, respectively. The degeneration of PCL was graded as follows: one, three, and 17 mild, moderate, and severe cases at the proximal portion, and 16, 4, and one mild, moderate, and severe cases at the distal portion, respectively. The radiological classification and the grade of degeneration were not correlated in either the proximal (r = 0.047, p = 0.84) or the distal (r = − 0.21, p = 0.35) portions. The HU value was 84.5, 72.1, and 70.6 HU for mild, moderate, and severe grades, respectively (mild versus moderate: p < 0.05, mild versus severe: p < 0.05, moderate versus severe: p > 0.05). CONCLUSIONS: In knee OA, a lower HU value in the PCL indicates the progression of degeneration. The CT HU value could be a useful measurement to predict the grade of PCL degeneration. BioMed Central 2021-03-26 /pmc/articles/PMC8004421/ /pubmed/33771140 http://dx.doi.org/10.1186/s12891-021-04177-w Text en © The Author(s) 2021 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Research Article Sumida, Yoshikazu Nakasa, Tomoyuki Ishikawa, Masakazu Nakamae, Atsuo Adachi, Nobuo The evaluation of degeneration of posterior cruciate ligament using CT Hounsfield unit in knee osteoarthritis |
title | The evaluation of degeneration of posterior cruciate ligament using CT Hounsfield unit in knee osteoarthritis |
title_full | The evaluation of degeneration of posterior cruciate ligament using CT Hounsfield unit in knee osteoarthritis |
title_fullStr | The evaluation of degeneration of posterior cruciate ligament using CT Hounsfield unit in knee osteoarthritis |
title_full_unstemmed | The evaluation of degeneration of posterior cruciate ligament using CT Hounsfield unit in knee osteoarthritis |
title_short | The evaluation of degeneration of posterior cruciate ligament using CT Hounsfield unit in knee osteoarthritis |
title_sort | evaluation of degeneration of posterior cruciate ligament using ct hounsfield unit in knee osteoarthritis |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8004421/ https://www.ncbi.nlm.nih.gov/pubmed/33771140 http://dx.doi.org/10.1186/s12891-021-04177-w |
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