Much ado about nothing? Off-target amplification can lead to false-positive bacterial brain microbiome detection in healthy and Parkinson’s disease individuals

BACKGROUND: Recent studies suggested the existence of (poly-)microbial infections in human brains. These have been described either as putative pathogens linked to the neuro-inflammatory changes seen in Parkinson’s disease (PD) and Alzheimer’s disease (AD) or as a “brain microbiome” in the context o...

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Detalles Bibliográficos
Autores principales: Bedarf, Janis R., Beraza, Naiara, Khazneh, Hassan, Özkurt, Ezgi, Baker, David, Borger, Valeri, Wüllner, Ullrich, Hildebrand, Falk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8004470/
https://www.ncbi.nlm.nih.gov/pubmed/33771222
http://dx.doi.org/10.1186/s40168-021-01012-1

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