Phosphatidylinositol 4-kinase IIIβ mediates contraction-induced GLUT4 translocation and shows its anti-diabetic action in cardiomyocytes

In the diabetic heart, long-chain fatty acid (LCFA) uptake is increased at the expense of glucose uptake. This metabolic shift ultimately leads to insulin resistance and a reduced cardiac function. Therefore, signaling kinases that mediate glucose uptake without simultaneously stimulating LCFA uptak...

Descripción completa

Detalles Bibliográficos
Autores principales: Sun, A., Simsek Papur, O., Dirkx, E., Wong, L., Sips, T., Wang, S., Strzelecka, A., Nabben, M., Glatz, J. F. C., Neumann, D., Luiken, J. J. F. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8004495/
https://www.ncbi.nlm.nih.gov/pubmed/33090289
http://dx.doi.org/10.1007/s00018-020-03669-7

Ejemplares similares

Ejemplares similares