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Dual role of ER stress in response to metabolic co-targeting and radiosensitivity in head and neck cancer cells

Arginine deprivation therapy (ADT) is a new metabolic targeting approach with high therapeutic potential for various solid cancers. Combination of ADT with low doses of the natural arginine analog canavanine effectively sensitizes malignant cells to irradiation. However, the molecular mechanisms det...

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Detalles Bibliográficos
Autores principales:	Chen, Oleg, Manig, Friederike, Lehmann, Loreen, Sorour, Nagwa, Löck, Steffen, Yu, Zhanru, Dubrovska, Anna, Baumann, Michael, Kessler, Benedikt M., Stasyk, Oleh, Kunz-Schughart, Leoni A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2020
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8004506/ https://www.ncbi.nlm.nih.gov/pubmed/33230565 http://dx.doi.org/10.1007/s00018-020-03704-7

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