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Growth cone repulsion to Netrin-1 depends on lipid raft microdomains enriched in UNC5 receptors
During brain development, Uncoordinated locomotion 5 (UNC5) receptors control axonal extension through their sensing of the guidance molecule Netrin-1. The correct positioning of receptors into cholesterol-enriched membrane raft microdomains is crucial for the efficient transduction of the recognize...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8004515/ https://www.ncbi.nlm.nih.gov/pubmed/33095273 http://dx.doi.org/10.1007/s00018-020-03663-z |