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Utilizing an Animal Model to Identify Brain Neurodegeneration-Related Biomarkers in Aging

Glycine N-methyltransferase (GNMT) regulates S-adenosylmethionine (SAMe), a methyl donor in methylation. Over-expressed SAMe may cause neurogenic capacity reduction and memory impairment. GNMT knockout mice (GNMT-KO) was applied as an experimental model to evaluate its effect on neurons. In this stu...

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Detalles Bibliográficos
Autores principales:	Yang, Ming-Hui, Chen, Yi-Ming Arthur, Tu, Shan-Chen, Chi, Pei-Ling, Chuang, Kuo-Pin, Chang, Chin-Chuan, Lee, Chiang-Hsuan, Chen, Yi-Ling, Lee, Che-Hsin, Yuan, Cheng-Hui, Tyan, Yu-Chang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8004625/ https://www.ncbi.nlm.nih.gov/pubmed/33807010 http://dx.doi.org/10.3390/ijms22063278

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