Cargando…

A ROCK Inhibitor Promotes Graft Survival during Transplantation of iPS-Cell-Derived Retinal Cells

Currently, retinal pigment epithelium (RPE) transplantation includes sheet and single-cell transplantation, the latter of which includes cell death and may be highly immunogenic, and there are some issues to be improved in single-cell transplantation. Y-27632 is an inhibitor of Rho-associated protei...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ishida, Masaaki, Sugita, Sunao, Makabe, Kenichi, Fujii, Shota, Futatsugi, Yoko, Kamao, Hiroyuki, Yamasaki, Suguru, Sakai, Noriko, Maeda, Akiko, Mandai, Michiko, Takahashi, Masayo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8004718/ https://www.ncbi.nlm.nih.gov/pubmed/33810153 http://dx.doi.org/10.3390/ijms22063237

Ejemplares similares

A Strategy for Personalized Treatment of iPS-Retinal Immune Rejections Assessed in Cynomolgus Monkey Models
por: Fujii, Shota, et al.
Publicado: (2020)

Microglia dynamics in retinitis pigmentosa model: formation of fundus whitening and autofluorescence as an indicator of activity of retinal degeneration
por: Makabe, Kenichi, et al.
Publicado: (2020)

Retinal Pigment Epithelial Cells Derived from Induced Pluripotent Stem (iPS) Cells Suppress or Activate T Cells via Costimulatory Signals
por: Sugita, Sunao, et al.
Publicado: (2020)

Dynamics of Cyclooxygenase-1 Positive Microglia/Macrophage in the Retina of Pathological Model Mice as a Biomarker of the Retinal Inflammatory Diseases
por: Makabe, Kenichi, et al.
Publicado: (2021)

Characterization of Human Induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelium Cell Sheets Aiming for Clinical Application
por: Kamao, Hiroyuki, et al.
Publicado: (2014)

Detection of Retinal Pigment Epithelium-Specific Antibody in iPSC-Derived Retinal Pigment Epithelium Transplantation Models
por: Sugita, Sunao, et al.
Publicado: (2017)

Low Immunogenicity and Immunosuppressive Properties of Human ESC- and iPSC-Derived Retinas
por: Yamasaki, Suguru, et al.
Publicado: (2021)

Successful Transplantation of Retinal Pigment Epithelial Cells from MHC Homozygote iPSCs in MHC-Matched Models
por: Sugita, Sunao, et al.
Publicado: (2016)

Competency of iPSC-derived retinas in MHC-mismatched transplantation in non-human primates
por: Uyama, Hirofumi, et al.
Publicado: (2022)

Inhibition of T cell-mediated inflammation in uveitis by a novel anti-CD3 antibody
por: Sugita, Sunao, et al.
Publicado: (2017)

HLA-Matched Allogeneic iPS Cells-Derived RPE Transplantation for Macular Degeneration
por: Sugita, Sunao, et al.
Publicado: (2020)

Capacity of Retinal Ganglion Cells Derived from Human Induced Pluripotent Stem Cells to Suppress T-Cells
por: Edo, Ayaka, et al.
Publicado: (2020)

Detection of Mycoplasma Contamination in Transplanted Retinal Cells by Rapid and Sensitive Polymerase Chain Reaction Test
por: Sugita, Sunao, et al.
Publicado: (2021)

Tumorigenicity Studies of Induced Pluripotent Stem Cell (iPSC)-Derived Retinal Pigment Epithelium (RPE) for the Treatment of Age-Related Macular Degeneration
por: Kanemura, Hoshimi, et al.
Publicado: (2014)

Lack of T Cell Response to iPSC-Derived Retinal Pigment Epithelial Cells from HLA Homozygous Donors
por: Sugita, Sunao, et al.
Publicado: (2016)

Addition of Chk1 inhibitor and BMP4 cooperatively promotes retinal tissue formation in self-organizing human pluripotent stem cell differentiation culture
por: Yamasaki, Suguru, et al.
Publicado: (2022)

Proliferation Potential of Müller Glia after Retinal Damage Varies between Mouse Strains
por: Suga, Akiko, et al.
Publicado: (2014)

Polarization-sensitive optical coherence tomography for estimating relative melanin content of autologous induced stem-cell derived retinal pigment epithelium
por: Matsuzaki, Mitsuhiro, et al.
Publicado: (2020)

Establishment of Immunodeficient Retinal Degeneration Model Mice and Functional Maturation of Human ESC-Derived Retinal Sheets after Transplantation
por: Iraha, Satoshi, et al.
Publicado: (2018)

Differentiation/Purification Protocol for Retinal Pigment Epithelium from Mouse Induced Pluripotent Stem Cells as a Research Tool
por: Iwasaki, Yuko, et al.
Publicado: (2016)

Trends of Stem Cell Therapies in Age-Related Macular Degeneration
por: Maeda, Tadao, et al.
Publicado: (2021)

Human iPS cell derived RPE strips for secure delivery of graft cells at a target place with minimal surgical invasion
por: Nishida, Mitsuhiro, et al.
Publicado: (2021)

Detailed Evaluation of Chromatic Pupillometry and Full-Field Stimulus Testing to Assess Ultralow Vision in Retinitis Pigmentosa
por: Yamamoto, Midori, et al.
Publicado: (2023)

Immunological Properties of Neural Crest Cells Derived from Human Induced Pluripotent Stem Cells
por: Fujii, Shota, et al.
Publicado: (2019)

Retinitis Pigmentosa with EYS Mutations Is the Most Prevalent Inherited Retinal Dystrophy in Japanese Populations
por: Arai, Yuuki, et al.
Publicado: (2015)

Physiological Characterisation of Human iPS-Derived Dopaminergic Neurons
por: Hartfield, Elizabeth M., et al.
Publicado: (2014)

Evaluation of micro Electroretinograms Recorded with Multiple Electrode Array to Assess Focal Retinal Function
por: Fujii, Momo, et al.
Publicado: (2016)

A CASE OF RAPIDLY PROGRESSIVE RETINOPATHY ASSOCIATED WITH PEMBROLIZUMAB IMMUNOTHERAPY FOR METASTATIC UROTHELIAL CARCINOMA
por: Sakai, Daiki, et al.
Publicado: (2023)

A Genetic modification that reduces ON-bipolar cells in hESC-derived retinas enhances functional integration after transplantation
por: Yamasaki, Suguru, et al.
Publicado: (2021)

Publisher Correction: Preconditioning the Initial State of Feeder-free Human Pluripotent Stem Cells Promotes Self-formation of Three-dimensional Retinal Tissue
por: Kuwahara, Atsushi, et al.
Publicado: (2020)

Preconditioning the Initial State of Feeder-free Human Pluripotent Stem Cells Promotes Self-formation of Three-dimensional Retinal Tissue
por: Kuwahara, Atsushi, et al.
Publicado: (2019)

ROCK Inhibitor-Induced Promotion of Retinal Pigment Epithelial Cell Motility during Wound Healing
por: Kamao, Hiroyuki, et al.
Publicado: (2019)

Stem‐cell‐based therapies for retinal degenerative diseases: Current challenges in the establishment of new treatment strategies
por: Uyama, Hirofumi, et al.
Publicado: (2021)

Pigment Epithelium-Derived Factor Secreted from Retinal Pigment Epithelium Facilitates Apoptotic Cell Death of iPSC
por: Kanemura, Hoshimi, et al.
Publicado: (2013)

Retinal pigment epithelium melanin imaging using polarization-sensitive optical coherence tomography for patients with retinitis pigmentosa
por: Sakai, Daiki, et al.
Publicado: (2022)

Drug-Induced Naïve iPS Cells Exhibit Better Performance than Primed iPS Cells with Respect to the Ability to Differentiate into Pancreatic β-Cell Lineage
por: Kiyokawa, Yuki, et al.
Publicado: (2020)

The Exciting Realities and Possibilities of iPS-Derived Cardiomyocytes
por: Takahashi, Fuga, et al.
Publicado: (2023)

Assessment of the deformation of the outer nuclear layer in the Epiretinal membrane using spectral-domain optical coherence tomography
por: Takagi, Seiji, et al.
Publicado: (2019)

Beyond iPS!
Publicado: (2012)

Current Application of iPS Cells in the Dental Tissue Regeneration
por: Hamano, Sayuri, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_m51jodo47q1g37cn4ek9q7joed