Cross-Resistance to Abiraterone and Enzalutamide in Castration Resistance Prostate Cancer Cellular Models Is Mediated by AR Transcriptional Reactivation

SIMPLE SUMMARY: Prostate cancer is the second most common cancer in males. In prostate cancer cells, androgens bind and activate the intracellular mediator called Androgen Receptor that control cell proliferation and survival. Hormone deprivation therapy is administrated to reduce androgen levels an...

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Detalles Bibliográficos
Autores principales: Simon, Iris, Perales, Sonia, Casado-Medina, Laura, Rodríguez-Martínez, Alba, Garrido-Navas, Maria del Carmen, Puche-Sanz, Ignacio, Diaz-Mochon, Juan J., Alaminos, Clara, Lupiañez, Pablo, Lorente, Jose A., Serrano, María J., Real, Pedro J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8004828/
https://www.ncbi.nlm.nih.gov/pubmed/33807106
http://dx.doi.org/10.3390/cancers13061483

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