Selective Synthesis of N-Acylnortropane Derivatives in Palladium-Catalysed Aminocarbonylation

The aminocarbonylation of various alkenyl and (hetero)aryl iodides was carried out using tropane-based amines of biological importance, such as 8-azabicyclo[3.2.1]octan-3-one (nortropinone) and 3α-hydroxy-8-azabicyclo[3.2.1]octane (nortropine) as N-nucleophile. Using iodoalkenes, the two nucleophile...

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Detalles Bibliográficos
Autores principales: Kollár, László, Erdélyi, Ádám, Rasheed, Haroon, Takács, Attila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8004868/
https://www.ncbi.nlm.nih.gov/pubmed/33807018
http://dx.doi.org/10.3390/molecules26061813

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8004868/
https://www.ncbi.nlm.nih.gov/pubmed/33807018
http://dx.doi.org/10.3390/molecules26061813

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