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A Profound Basic Characterization of eIFs in Gliomas: Identifying eIF3I and 4H as Potential Novel Target Candidates in Glioma Therapy
SIMPLE SUMMARY: Gliomas are brain tumors with currently limited therapy options. Glioma growth and proliferation is regulated by the mTOR pathway together with eukaryotic initiation factors (eIFs). In this work we show a profound basic characterization of eIFs in human gliomas and demonstrate increa...
Autores principales: | Krassnig, Stefanie, Wohlrab, Christina, Golob-Schwarzl, Nicole, Raicht, Andrea, Schatz, Christoph, Birkl-Toeglhofer, Anna Maria, Skofler, Christina, Gantenbein, Nadine, Leoni, Marlene, Asslaber, Martin, Leber, Stefan L., Mahdy-Ali, Kariem, von Campe, Gord, Mayer, Marlene, Borenich, Andrea, Weis, Serge, Benesch, Martin, Haybaeck, Johannes |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8004965/ https://www.ncbi.nlm.nih.gov/pubmed/33807050 http://dx.doi.org/10.3390/cancers13061482 |
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